Suppr超能文献

75岁以上患者冠状动脉旁路移植术的良好结果。

Favorable results of coronary artery bypass grafting in patients older than 75 years.

作者信息

Horvath K A, DiSesa V J, Peigh P S, Couper G S, Collins J J, Cohn L H

机构信息

Division of Cardiac Surgery, Brigham and Women's Hospital, Boston, MA 02115.

出版信息

J Thorac Cardiovasc Surg. 1990 Jan;99(1):92-5; discussion 95-6.

PMID:2294368
Abstract

There is controversy whether the short-term and long-term results of coronary artery bypass grafting in elderly patients justify performing the procedure. Between January 1977 and December 1986, 4580 patients underwent coronary artery bypass grafting, of whom 222 (4.9%) were 75 years old or older (mean 77 years). There were 143 men and 79 women and 139 (63%) were in New York Heart Association class IV. One hundred forty-six patients (66%) had had at least one preoperative myocardial infarction. Myocardial revascularization was performed under emergency conditions in 17 patients (18%). The mammary artery was used in 43%, 96% of the patients received two or more grafts. The mean number of bypass grafts was 3.1 per patient. The overall hospital mortality rate was 10.8% (24/222), 3.6% for elective procedures, 14.9% in urgent cases, and 35% in emergencies. In contrast, the overall early mortality rate was 3.1% in 4358 patients less than 75 years old. Complications occurred in 83 patients (37%). Of the patients discharged from the hospital, 198 were followed up for a mean of 48 months (1 to 130). Actuarial probability of survival was 75% at 48 months. Postoperatively 70% were in New York Heart Association class I or II and only 21% were rehospitalized for cardiac problems. During the follow-up period 77% of the patients were free from angina, and of those experiencing angina the mean time from operation to the first episode was 75 months. Although elderly patients have a somewhat increased operative mortality rate, particularly if operated on urgently or emergently, long-term survival and freedom from angina are excellent and justify continued performance of coronary bypass grafting in selected patients over 75 years of age.

摘要

老年患者冠状动脉搭桥术的短期和长期效果是否足以证明该手术的合理性存在争议。1977年1月至1986年12月期间,4580例患者接受了冠状动脉搭桥术,其中222例(4.9%)年龄在75岁及以上(平均77岁)。男性143例,女性79例,139例(63%)属于纽约心脏协会IV级。146例患者(66%)术前至少发生过一次心肌梗死。17例患者(18%)在紧急情况下进行了心肌血运重建。43%的患者使用了乳内动脉,96%的患者接受了两个或更多的移植血管。每位患者的平均搭桥血管数为3.1支。总体医院死亡率为10.8%(24/222),择期手术为3.6%,急症手术为14.9%,急诊手术为35%。相比之下,4358例75岁以下患者的总体早期死亡率为3.1%。83例患者(37%)出现并发症。出院患者中,198例接受了平均48个月(1至130个月)的随访。48个月时的生存 actuarial 概率为75%。术后70%的患者属于纽约心脏协会I级或II级,只有21%因心脏问题再次住院。在随访期间,77%的患者无心绞痛,有心绞痛的患者从手术到首次发作的平均时间为75个月。尽管老年患者的手术死亡率有所增加,尤其是在急症或急诊手术时,但长期生存和无心绞痛情况良好,证明在75岁以上的特定患者中继续进行冠状动脉搭桥术是合理的。

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验