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儿童心室梗阻性扩张与萎缩性扩张的鉴别

Distinction between obstructive and atrophic dilatation of ventricles in children.

作者信息

Heinz E R, Ward A, Drayer B P, Dubois P J

出版信息

J Comput Assist Tomogr. 1980 Jun;4(3):320-5. doi: 10.1097/00004728-198006000-00006.

DOI:10.1097/00004728-198006000-00006
PMID:6966287
Abstract

The computed tomography (CT) scans of 92 infants and children were reviewed. Thirty-three had proven atrophy, and 44 had proven obstructive hydrocephalus. Twelve CT measurements were made, and the results were subjected to computer analysis. The pathologic patients were divided into three groups by ventricular size index: mild (33--39%), moderate (40--46%), and severe (greater than 46%) enlargement. Obstructive patients showed much greater measurements for the temporal horn diameter and the frontal horn radius. The angle of the frontal horn was narrower in the obstructed group than in the atrophic patients. As expected, there were significantly more sulci visualized in the atrophic group than in the obstructed group. Three of these four parameters were directly related to concentric expansion of the ventricles in the presence of obstructive hydrocephalus. This is contrasted with passive dilatation of the ventricular system with preservation of the normal ventricular configuration in atrophy. The temporal horn diameter, frontal horn radius, the angle of the frontal horn, and the number of sulci all distinguish between obstruction and atrophy with individual probabilities of less than 0.05. When used together, they assure a high probability of separating obstruction from atrophy. Preliminary data suggest that these findings may have application in adults, but the number of confirmed observations has been too small for statistical analysis.

摘要

对92例婴幼儿和儿童的计算机断层扫描(CT)进行了回顾性分析。其中33例证实有萎缩,44例证实有梗阻性脑积水。进行了12项CT测量,并对结果进行了计算机分析。根据脑室大小指数,将病理患者分为三组:轻度(33%-39%)、中度(40%-46%)和重度(大于46%)扩大。梗阻性脑积水患者的颞角直径和额角半径测量值明显更大。梗阻组的额角角度比萎缩组更窄。正如预期的那样,萎缩组比梗阻组可见的脑沟明显更多。这四个参数中的三个与梗阻性脑积水时脑室的同心扩张直接相关。这与萎缩时脑室系统的被动扩张形成对比,萎缩时脑室系统保持正常的脑室形态。颞角直径、额角半径、额角角度和脑沟数量都能区分梗阻和萎缩,其个体概率均小于0.05。综合使用时,它们能确保将梗阻与萎缩区分开来的概率很高。初步数据表明,这些发现可能适用于成年人,但已确认的观察数量过少,无法进行统计分析。

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Comparative study of subcortical atrophy in patients with frontotemporal dementia and dementia with extrapyramidal signs.额颞叶痴呆和伴有锥体外系症状的痴呆患者皮质下萎缩的比较研究。
Clin Pract Epidemiol Ment Health. 2015 Mar 31;11:125-9. doi: 10.2174/1745017901511010125. eCollection 2015.
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Morphometric study of the midsagittal MR imaging plane in cases of hydrocephalus and atrophy and in normal brains.
脑积水、萎缩病例及正常脑的矢状面正中磁共振成像平面的形态学研究。
AJNR Am J Neuroradiol. 2001 Oct;22(9):1674-9.
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A comparative study of linear measurement of the brain and three-dimensional measurement of brain volume using CT scans.一项使用CT扫描对大脑进行线性测量和三维体积测量的对比研究。
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