Collewijn H, Verhagen A M, Grootendorst A F
Brain Res. 1980 Jun 23;192(2):305-12. doi: 10.1016/0006-8993(80)90885-9.
Horizontal optokinetic reflexes (OKN) are inverted in an anterior (90-180 degrees) sector of the visual field in albino rabbits. We investigated whether the inverted processing of direction-selective information would affect long-term adaptation of the vestibulo-ocular reflex (VOR). Normal posterior parts of the visual fields were masked for periods up to 80 days. The inversion of OKN, with instability of the eyes and head in the light, was not corrected in this period. The amplitude of the VOR was progressively reduced, but a true inversion was not achieved. Recovery was seen after removal of the masks. These changes were larger and more consistent in Himalayan than in Polish rabbits. Normal, Dutch pigmented rabbits which served as controls showed no significant reduction of VOR gain. Phase lead of the VOR for low stimulus frequencies increased in both pigmented and albino rabbits. In short-term experiments with forced oscillation, similar but smaller changes were observed.
在白化兔中，水平视动反射（OKN）在视野的前侧（90 - 180度）扇形区域是倒置的。我们研究了方向选择性信息的倒置处理是否会影响前庭眼反射（VOR）的长期适应性。正常视野的后部被遮盖长达80天。在此期间，OKN的倒置以及在光照下眼睛和头部的不稳定并未得到纠正。VOR的幅度逐渐减小，但并未实现真正的倒置。去除遮盖物后可见恢复。这些变化在喜马拉雅兔中比在波兰兔中更大且更一致。作为对照的正常荷兰有色兔的VOR增益没有显著降低。在有色兔和白化兔中，低刺激频率下VOR的相位超前均增加。在强迫振荡的短期实验中，观察到了类似但较小的变化。
