Ito M, Jastreboff P J, Miyashita Y
Exp Brain Res. 1979 Sep;37(1):17-30. doi: 10.1007/BF01474250.
Adaptability of the horizontal vestibulo-ocular reflex (HVOR) and the optokinetic response (OKR) was examined in alert albino rabbits during sustained runs lasting 5--12 h under four different stimulus conditions. (1) Sinusoidal rotation of the rabbit in darkness by 5 degrees at 1/10 Hz, or (2) sinusoidal movement of a vertical slit light by 2.5 degrees of 5 degrees at 1/10 Hz around the optical axis of the stationary rabbit, affected the gain of neither the HVOR nor the OKR. (3) Combination of the stimulus as in (1) with the stationary slit light increased the gain of the HVOR gradually. A plateau at about 140% of the initial control was reached in 5 h. (4) Combination of the stimulus as in (1) with the slit light movement by 10 degrees in phase with the turntable decreased the HVOR gain gradually, a plateau being obtained at about 70% of the initial control in 5 h. Changes of the HVOR gain induced in conditions (3) and (4) were not frequency-specific and accompanied by no signficant modification of either the gain or phase of the OKR or the linear property of HVOR-OKR interaction. A small but significant change of the HVOR phase was also detected under the condition (3) but not (4).
在四种不同刺激条件下，对清醒的白化兔在持续5 - 12小时的奔跑过程中，水平前庭眼反射（HVOR）和视动反应（OKR）的适应性进行了检测。（1）兔子在黑暗中以1/10赫兹的频率进行5度的正弦旋转，或者（2）在静止兔子的光轴周围，垂直狭缝光以1/10赫兹的频率进行2.5度或5度的正弦移动，这两种情况均未影响HVOR或OKR的增益。（3）将（1）中的刺激与静止的狭缝光相结合，会使HVOR的增益逐渐增加。在5小时内达到约初始对照值140%的平稳状态。（4）将（1）中的刺激与狭缝光以与转盘同相位的10度移动相结合，会使HVOR增益逐渐降低，在5小时内达到约初始对照值70%的平稳状态。在条件（3）和（4）中诱导的HVOR增益变化不是频率特异性的，并且OKR的增益或相位以及HVOR - OKR相互作用的线性特性均未发生显著改变。在条件（3）下还检测到HVOR相位有微小但显著的变化，但在条件（4）下未检测到。
