Wen H L, Ho W K, Ling N, Mehal Z D, Ng Y H
Am J Chin Med. 1980 Spring-Summer;8(1-2):154-9. doi: 10.1142/s0192415x80000104.
The present study was undertaken to evaluate if plasma or CSF beta-endorphin level can be induced to rise during the treatment of heroin addiction by electroacupuncture. Based on the examination of 30 addicts, we obtained no evidence indicating an increase of beta-endorphin level in either the plasma or the CSF after 30 min of acupuncture. In spite of this, the majority of the addicts experienced a reduction of withdrawal symptoms during treatment. Since electroacupuncture may only induce a highly localized secretion of beta-endorphin in the brain, our results cannot unequivocally exclude the possibility that this peptide is involved in mediating the action of acupuncture.
本研究旨在评估电针治疗海洛因成瘾过程中血浆或脑脊液β-内啡肽水平是否会升高。通过对30名成瘾者的检测，我们未发现针刺30分钟后血浆或脑脊液中β-内啡肽水平升高的证据。尽管如此，大多数成瘾者在治疗过程中戒断症状有所减轻。由于电针可能仅诱导大脑中β-内啡肽的高度局部性分泌，我们的结果不能明确排除这种肽参与介导针刺作用的可能性。
