Wells J V, King M A
Anaesth Intensive Care. 1980 May;8(2):139-44. doi: 10.1177/0310057X8000800207.
Adverse reactions to human plasma proteins range from mild urticaria to fatal anaphylaxis and may occur with virtually any blood product. The most common clinical settings appear to be whole blood transfusion in subjects with no previous history of reactions, or the infusion of fresh frozen plasma or injection of human immune serum globulin (HISG) to patients with known immunodeficiency. The immunological processes involved and the management of reactions are discussed.
对人血浆蛋白的不良反应范围从轻度荨麻疹到致命性过敏反应,几乎任何血液制品都可能发生。最常见的临床情况似乎是既往无反应史的受试者接受全血输血,或向已知免疫缺陷患者输注新鲜冰冻血浆或注射人免疫血清球蛋白(HISG)。文中讨论了所涉及的免疫过程及反应的处理。