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流感嗜血杆菌中无突变伴随的可诱导修复系统。

Inducible repair system in Haemophilus influenzae unaccompanied by mutation.

作者信息

Notani N K, Setlow J K

出版信息

J Bacteriol. 1980 Jul;143(1):516-9. doi: 10.1128/jb.143.1.516-519.1980.

Abstract

Weigle reactivation of ultraviolet-irradiated HPlc1 phage was observed after ultraviolet or mitomycin C treatment of Haemophilus influenzae cells. The amount of reactivation was considerably increased when the treated cells were incubated in growth medium before infection. The presence of chloramphenicol during this incubation abolished the reactivation. No mutation of this phage accompanied the reactivation. When cells were treated so as to produce a maximal reactivation of phage, neither reactivation or mutation of cells was observed. It is concluded that H. influenzae has an inducible repair system that is not accompanied by mutation.

摘要

在对流感嗜血杆菌细胞进行紫外线或丝裂霉素C处理后,观察到紫外线照射的HPlc1噬菌体出现了韦格勒复活现象。当处理后的细胞在感染前于生长培养基中孵育时,复活量显著增加。在此孵育过程中加入氯霉素会消除复活现象。这种噬菌体的复活不伴有突变。当对细胞进行处理以产生噬菌体的最大复活时,未观察到细胞的复活或突变。结论是流感嗜血杆菌具有一种不伴有突变的可诱导修复系统。

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