Bar-Sela S, Levo Y, Zeevi D, Slavin S, Eliakim M
J Rheumatol. 1980 May-Jun;7(3):379-80.
A patient with degenerative joint disease with an unusual hypersensitivity reaction to ibuprofen is described. The patient developed transient fever, myalgia polyarthritis and rash following each of 4 exposures to the drug. These manifestations were associated with positive Coombs' and FANA tests.