随着年龄增长免疫能力的丧失可能归因于自身抗独特型抗体调节。 - Suppr

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超能文献

Loss of immune competence with age may be due to auto-anti-idiotypic antibody regulation.

作者信息

Szewczuk M R, Campbell R J

出版信息

Nature. 1980 Jul 10;286(5769):164-6. doi: 10.1038/286164a0.

DOI:10.1038/286164a0

PMID:6967565

Abstract

摘要

相似文献

Loss of immune competence with age may be due to auto-anti-idiotypic antibody regulation.随着年龄增长免疫能力的丧失可能归因于自身抗独特型抗体调节。

Nature. 1980 Jul 10;286(5769):164-6. doi: 10.1038/286164a0.

Production of auto-anti-idiotypic antibody during the normal immune response: changes in the auto-anti-idiotypic antibody response and the idiotype repertoire associated with aging.正常免疫反应过程中自身抗独特型抗体的产生：与衰老相关的自身抗独特型抗体反应及独特型库的变化。

Proc Natl Acad Sci U S A. 1980 Nov;77(11):6788-92. doi: 10.1073/pnas.77.11.6788.

Idiotype-directed interactions during ontogeny play a major role in the establishment of the adult B cell repertoire.个体发育过程中独特型导向的相互作用在成年B细胞库的建立中起主要作用。

Immunol Rev. 1986 Dec;94:39-50. doi: 10.1111/j.1600-065x.1986.tb01163.x.

Autoantiidiotypic immunization and transplantation tolerance in the primate.

Transplant Proc. 1979 Mar;11(1):923-7.

Production of auto-anti-idiotypic antibody during the normal immune response to TNP-Ficoll. II. Hapten-reversible inhibition of anti-TNP plaque-forming cells by immune serum as an assay for auto-anti-idiotypic antibody.对三硝基苯-聚蔗糖（TNP-Ficoll）正常免疫应答过程中自身抗独特型抗体的产生。II. 用免疫血清对半抗原可逆性抑制抗TNP噬斑形成细胞进行检测以测定自身抗独特型抗体

J Exp Med. 1979 Jul 1;150(1):154-65. doi: 10.1084/jem.150.1.154.

Idiotypic-antiidiotypic interactions in humans.人类中的独特型-抗独特型相互作用。

J Biol Response Mod. 1984 Dec;3(6):573-9.

The B-cell clonotype repertoire.B细胞克隆型库

Adv Immunol. 1978;26:255-337. doi: 10.1016/s0065-2776(08)60232-1.

Identification and characterization of an apparent germline set of auto-anti-idiotypic regulatory B lymphocytes.一种明显的种系自身抗独特型调节性B淋巴细胞的鉴定与表征。

J Immunol. 1984 Jan;132(1):114-21.

Structural and biological properties of a monoclonal auto-anti-(anti-idiotype) antibody.一种单克隆自身抗（抗独特型）抗体的结构与生物学特性

Nature. 1982 Sep 30;299(5882):447-9. doi: 10.1038/299447a0.

Perturbation of the autoimmune network. II. Immunization with isologous idiotype induces auto-anti-idiotypic antibodies and suppresses the autoantibody response elicited by antigen: a serologic and cellular analysis.自身免疫网络的扰动。II. 用同种型独特型进行免疫诱导自身抗独特型抗体并抑制抗原引发的自身抗体反应：血清学和细胞分析。

J Immunol. 1986 Nov 15;137(10):3140-6.

引用本文的文献

Autologous anti-idiotypic antibody response is regulated by the level of circulating complementary idiotype.自体抗独特型抗体反应受循环互补独特型水平的调节。

Immunology. 1996 Oct;89(2):172-7. doi: 10.1046/j.1365-2567.1996.d01-724.x.

In vivo and in vitro study of the primary and secondary antibody response to a bacterial antigen in aged mice.老年小鼠对细菌抗原的初次和二次抗体反应的体内和体外研究。

Int J Exp Pathol. 1995 Dec;76(6):419-24.

Natural H-2-specific antibodies in sera of aged mice.老年小鼠血清中的天然H-2特异性抗体。

Immunogenetics. 1982 Jan;15(1):95-102. doi: 10.1007/BF00375506.

Loss of tumor-specific and idiotype-specific immunity with age.随着年龄增长，肿瘤特异性和独特型特异性免疫力丧失。

J Exp Med. 1981 Aug 1;154(2):275-90. doi: 10.1084/jem.154.2.275.

Proc Natl Acad Sci U S A. 1980 Nov;77(11):6788-92. doi: 10.1073/pnas.77.11.6788.

Production of auto-antiidiotypic antibody during the normal immune response. VII. Analysis of the cellular basis for the increased auto-antiidiotype antibody production by aged mice.正常免疫反应过程中自身抗独特型抗体的产生。VII. 对衰老小鼠自身抗独特型抗体产生增加的细胞基础的分析。

J Exp Med. 1983 May 1;157(5):1635-45. doi: 10.1084/jem.157.5.1635.

Immunoregulation in senescence: increased inducibility of antigen-specific suppressor T cells and loss of cell sensitivity to immunosuppression in aging mice.衰老过程中的免疫调节：衰老小鼠体内抗原特异性抑制性T细胞的诱导能力增强以及细胞对免疫抑制的敏感性丧失。

Proc Natl Acad Sci U S A. 1982 Jun;79(12):3803-7. doi: 10.1073/pnas.79.12.3803.

Antigenicity, storage, and aging: physiologic autoantibodies to cell membrane and serum proteins and the senescent cell antigen.抗原性、储存与老化：针对细胞膜及血清蛋白的生理性自身抗体和衰老细胞抗原

Mol Cell Biochem. 1982 Nov 26;49(2):65-85. doi: 10.1007/BF00242486.

Effects of antigen and internal environment on anti-phosphorylcholine immune responses of autoimmune aged NZB/W F1 mice.抗原和内环境对自身免疫性老年NZB/W F1小鼠抗磷酸胆碱免疫反应的影响。

Immunology. 1986 Jun;58(2):329-34.

Production of auto-anti-idiotype antibody during the normal immune response. XIV. Evidence for the antigen-independent operation of the idiotype network.正常免疫反应过程中自身抗独特型抗体的产生。十四、独特型网络抗原非依赖性运作的证据。

Immunology. 1989 Jun;67(2):191-6.

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