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大鼠乳糜管淋巴细胞含量分析。

An analysis of the lymphocyte content of rat lacteals.

作者信息

Steer H W

出版信息

J Immunol. 1980 Oct;125(4):1845-8.

PMID:6967919
Abstract

A technique for the collection of lymph from the lacteals of the small intestine of the rat is described. The output of lymphocytes from an area possessing a Peyer's patch is 10 times greater than in lymph from an area lacking one, but the proportion of lymphocytes with surface immunoglobulin (sIg), surface immunoglobulin A (sIgA), and internal immunoglobulin A (iIgA) are similar in the 2 areas. A lower percentage of lymphocytes bear sIg in lymph afferent to the mesenteric lymph gland compared with that found in the thoracic duct. However, a higher proportion of these lymphocytes bearing sIg have IgA on their surface in lacteal lymph compared with thoracic duct lymph. The reasons for these differences between the lacteal lymph and thoracic duct lymph are discussed.

摘要

本文描述了一种从大鼠小肠乳糜管收集淋巴液的技术。具有派尔集合淋巴结区域的淋巴细胞输出量比缺乏该结构区域的淋巴液中的淋巴细胞输出量大10倍,但这两个区域中具有表面免疫球蛋白(sIg)、表面免疫球蛋白A(sIgA)和内部免疫球蛋白A(iIgA)的淋巴细胞比例相似。与胸导管中的淋巴细胞相比,肠系膜淋巴结传入淋巴中带有sIg的淋巴细胞百分比更低。然而,与胸导管淋巴相比,乳糜管淋巴中这些带有sIg的淋巴细胞表面具有IgA的比例更高。文中讨论了乳糜管淋巴和胸导管淋巴之间这些差异的原因。

相似文献

1
An analysis of the lymphocyte content of rat lacteals.大鼠乳糜管淋巴细胞含量分析。
J Immunol. 1980 Oct;125(4):1845-8.
2
Intraepithelial, lamina propria and Peyer's patch lymphocytes of the rat small intestine: isolation and characterization in terms of immunoglobulin markers and receptors for monoclonal antibodies.大鼠小肠上皮内、固有层和派尔集合淋巴结淋巴细胞:根据免疫球蛋白标记物和单克隆抗体受体进行分离与特性鉴定
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A population of resting IgM-IgD double-bearing lymphocytes in Peyer's patches: the major precursor cells for IgA plasma cells in the gut lamina propria.派尔集合淋巴结中存在一群静息的IgM-IgD双阳性淋巴细胞:它们是肠道固有层中IgA浆细胞的主要前体细胞。
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Peyer's patch lymphocytes: demonstration of the integrity of afferent and efferent T-cell functions in the guinea pig and rat.派尔集合淋巴结淋巴细胞:豚鼠和大鼠传入及传出T细胞功能完整性的证明
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Surface phenotype of Peyer's patch germinal center cells: implications for the role of germinal centers in B cell differentiation.派尔集合淋巴结生发中心细胞的表面表型:对生发中心在B细胞分化中作用的启示
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Peyer's patches export lymphocytes throughout the lymphoid system in sheep.派尔集合淋巴结将淋巴细胞输送到绵羊的整个淋巴系统。
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Effect of vitamin E supplementation on lymphocyte distribution in gut-associated lymphoid tissues obtained from weaned piglets.维生素E补充剂对断奶仔猪肠道相关淋巴组织中淋巴细胞分布的影响。
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Studies on the lymphocytes of sheep. III. Destination of lymph-borne immunoblasts in relation to their tissue of origin.绵羊淋巴细胞研究。III. 淋巴源性免疫母细胞与其起源组织相关的归宿
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The distribution of a rabbit thymic antigen and membrane immunoglobulins in lymphoid tissue, with special reference to mucosal lymphocytes.兔胸腺抗原与膜免疫球蛋白在淋巴组织中的分布,特别涉及黏膜淋巴细胞
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The gut-associated lymphoid system: nature and properties of the large dividing cells.肠道相关淋巴系统:大型分裂细胞的性质与特征
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引用本文的文献

1
Effects of the expansion of bacterial colonies into the intervillous spaces on the localization of several lymphocyte lineages in the rat ileum.细菌菌落扩展至绒毛间隙对大鼠回肠中几种淋巴细胞谱系定位的影响。
J Vet Med Sci. 2019 Apr 16;81(4):555-566. doi: 10.1292/jvms.18-0734. Epub 2019 Feb 25.
2
Increased proliferative response of lymphocytes from intestinal lymph during long chain fatty acid absorption.长链脂肪酸吸收过程中肠道淋巴中淋巴细胞增殖反应增强。
Immunology. 1993 Jan;78(1):142-6.
3
Antigen processing: cultured lymph-borne dendritic cells can process and present native protein antigens.
抗原处理:培养的淋巴源性树突状细胞能够处理并呈递天然蛋白质抗原。
Immunology. 1995 Feb;84(2):241-6.
4
Study of acute localised inflammation of the gastrointestinal tract: the effluent lymph.胃肠道急性局限性炎症的研究:引流淋巴液
Gut. 1981 Oct;22(10):827-35. doi: 10.1136/gut.22.10.827.
5
Characterization of nonlymphoid cells derived from rat peripheral lymph.源自大鼠外周淋巴的非淋巴细胞的特性分析
J Exp Med. 1983 Jun 1;157(6):1758-79. doi: 10.1084/jem.157.6.1758.
6
Morphological alteration of gut-associated lymphoid tissue after long-term total parenteral nutrition in rats.大鼠长期全胃肠外营养后肠道相关淋巴组织的形态学改变
Cell Tissue Res. 1991 Oct;266(1):29-36. doi: 10.1007/BF00678708.