Suppr超能文献

正常小鼠的T细胞促进辐射诱导淋巴瘤的生长。

Enhancement of growth of a radiation-induced lymphoma by T cells from normal mice.

作者信息

Gabizon A, Trainin N

出版信息

Br J Cancer. 1980 Oct;42(4):551-8. doi: 10.1038/bjc.1980.279.

DOI:10.1038/bjc.1980.279
PMID:6969087
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2010444/
Abstract

The effect of lymphocytes from normal mice on the growth of a syngeneic, radiation-induced, T-cell-derived lymphoma was investigated. Thymus and spleen cells enhanced the growth of admixed lymphoma cells in a reproducible manner. Growth enhancement was manifested by the earlier appearance and higher final incidence of tumours. Lymphocytes also enhanced the growth of radiation-damaged lymphoma cells. The enhancing activity of spleen cells was predominantly a property of T cells, since it was abolished by treatment with anti-theta serum plus complement and significantly less in spleen cells of nude mice. Tumour-enhancing thymocytes seem to belong to the immature thymic subpopulation, as indicated by their binding to peanut agglutinin.

摘要

研究了正常小鼠淋巴细胞对同基因、辐射诱导的T细胞源性淋巴瘤生长的影响。胸腺细胞和脾细胞以可重复的方式促进了混合淋巴瘤细胞的生长。生长促进表现为肿瘤出现更早且最终发病率更高。淋巴细胞还促进了受辐射损伤的淋巴瘤细胞的生长。脾细胞的增强活性主要是T细胞的特性，因为用抗θ血清加补体处理可消除该活性，且裸鼠脾细胞中的活性明显较低。肿瘤增强性胸腺细胞似乎属于未成熟胸腺亚群，这可通过它们与花生凝集素的结合来表明。

相似文献

1
Enhancement of growth of a radiation-induced lymphoma by T cells from normal mice.正常小鼠的T细胞促进辐射诱导淋巴瘤的生长。
Br J Cancer. 1980 Oct;42(4):551-8. doi: 10.1038/bjc.1980.279.
2
Characterization of RFM mouse T lymphocyte anti-oncofetal antigen immunity in apparent tumor-free, long-term survivors of sublethal X-irradiation by limiting dilution T lymphocyte cloning.通过有限稀释T淋巴细胞克隆法对亚致死剂量X射线照射后长期存活且表面无肿瘤的RFM小鼠T淋巴细胞抗癌胚抗原免疫进行表征。
J Immunol. 1995 Mar 1;154(5):2266-80.
3
Inhibition of the growth of lymphoid tumours in syngeneic athymic (nude) mice.对同基因无胸腺（裸）小鼠体内淋巴瘤生长的抑制作用。
Int J Cancer. 1977 Jul 15;20(1):146-55. doi: 10.1002/ijc.2910200122.
4
Characteristics of the immature cells involved in T cell-mediated enhancement of syngeneic tumor growth.
J Immunol. 1977 May;118(5):1517-23.
5
In vitro reactivity of splenic lymphocytes from normal and UV-irradiated mice against syngeneic UV-induced tumors.正常小鼠和紫外线照射小鼠的脾淋巴细胞对同基因紫外线诱导肿瘤的体外反应性。
J Immunol. 1977 Apr;118(4):1483-7.
6
Inhibition of proliferation of lymphoma cells and T lymphocytes by suppressor cells from spleens of tumor-bearing mice.荷瘤小鼠脾脏抑制细胞对淋巴瘤细胞和T淋巴细胞增殖的抑制作用
J Immunol. 1975 Jan;114(1 Pt 1):206-10.
7
Effect of graft-versus-host reaction on the immune response to alloantigens and growth of a syngeneic tumor.移植物抗宿主反应对同种异体抗原免疫反应及同基因肿瘤生长的影响。
Exp Hematol. 1975 Jan;3(1):12-21.
8
Myeloid, B and T lymphoid and mixed lineage thymic lymphomas in the irradiated mouse.受辐照小鼠中的髓系、B和T淋巴细胞系以及混合谱系胸腺淋巴瘤
Carcinogenesis. 2002 Jun;23(6):1079-85. doi: 10.1093/carcin/23.6.1079.
9
Influence of presensitization with allogeneic lymphoma cells on the growth and response to therapy of radiation-induced lymphomas in mice.同种异体淋巴瘤细胞预致敏对小鼠辐射诱导淋巴瘤生长及治疗反应的影响。
Experientia. 1979 Aug 15;35(8):1098-9. doi: 10.1007/BF01949965.
10
In vitro stimulation and inhibition of tumor cell growth mediated by different lymphoid cell populations.不同淋巴细胞群体介导的肿瘤细胞生长的体外刺激与抑制
Cancer Res. 1977 May;37(5):1408-15.

引用本文的文献

1
Fabrication principles and their contribution to the superior in vivo therapeutic efficacy of nano-liposomes remote loaded with glucocorticoids.纳米脂质体远程加载糖皮质激素的构建原理及其对体内治疗效果的提升作用。
PLoS One. 2011;6(10):e25721. doi: 10.1371/journal.pone.0025721. Epub 2011 Oct 6.
2
Superior therapeutic activity of liposome-associated adriamycin in a murine metastatic tumour model.脂质体阿霉素在小鼠转移性肿瘤模型中的卓越治疗活性。
Br J Cancer. 1985 May;51(5):681-9. doi: 10.1038/bjc.1985.103.
3
Liposome formulations with prolonged circulation time in blood and enhanced uptake by tumors.具有延长的血液中循环时间和增强的肿瘤摄取能力的脂质体制剂。
Proc Natl Acad Sci U S A. 1988 Sep;85(18):6949-53. doi: 10.1073/pnas.85.18.6949.
4
Sterically stabilized liposomes: improvements in pharmacokinetics and antitumor therapeutic efficacy.空间稳定脂质体：药代动力学及抗肿瘤治疗效果的改善
Proc Natl Acad Sci U S A. 1991 Dec 15;88(24):11460-4. doi: 10.1073/pnas.88.24.11460.

本文引用的文献

1
Immune mechanisms in homotransplantation. II. Quantitative assay of the immunologic activity of lymphoid cells stimulated by tumor homografts.同种移植中的免疫机制。II. 肿瘤同种移植物刺激的淋巴细胞免疫活性的定量测定。
J Immunol. 1961 Feb;86:228-39.
2
Effect of lethally damaged tumor cells upon the development of admixed viable cells.致死性损伤的肿瘤细胞对混合的活细胞生长发育的影响。
J Natl Cancer Inst. 1958 Jun;20(6):1157-86.
3
Mouse thymic iso-antigens.小鼠胸腺同种抗原。
Nature. 1966 Jan 29;209(5022):521-3. doi: 10.1038/209521b0.
4
Facilitation of tumor growth by syngeneic normal cells mixed with tumor cells in vitro.体外将同基因正常细胞与肿瘤细胞混合对肿瘤生长的促进作用。
Cancer. 1971 Apr;27(4):897-901. doi: 10.1002/1097-0142(197104)27:4<897::aid-cncr2820270421>3.0.co;2-d.
5
Effects of intercellular contact on repair of radiation damage.细胞间接触对辐射损伤修复的影响。
Exp Cell Res. 1972 Mar;71(1):75-80. doi: 10.1016/0014-4827(72)90265-0.
6
The immune reaction as a stimulator of tumor growth.作为肿瘤生长刺激因素的免疫反应。
Science. 1972 Apr 14;176(4031):170-1. doi: 10.1126/science.176.4031.170.
7
Immune stimulation-inhibition of experimental cancer metastasis.
Cancer Res. 1974 Mar;34(3):491-8.
8
In vitro studies of cellular-mediated immunostimulation of tumor growth.
J Natl Cancer Inst. 1973 May;50(5):1307-12. doi: 10.1093/jnci/50.5.1307.
9
Immunological enhancement of tumor growth by syngeneic thymus-derived lymphocytes.
Transplantation. 1974 Sep;18(3):244-50. doi: 10.1097/00007890-197409000-00007.
10
EnhancemenT of 3LL tumor growth by autosensitized t lymphocytes independent of the host lymphatic system.自体致敏T淋巴细胞在不依赖宿主淋巴系统的情况下增强3LL肿瘤生长。
Int J Cancer. 1974 Aug 15;14(2):168-75. doi: 10.1002/ijc.2910140205.

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验