Bull World Health Organ. 1980;58(4):629-38.
In a rural community on the island of Luzon, Philippines, the overall prevalence of Schistosoma japonicum infection, based on stool examination performed by both a new modified quantitative thick smear and the merthiolate-iodine-formaldehyde concentration (MIFC) technique, was 49.5% in a total study population of 755 persons. Peak prevalence was observed in the 15-19-year age group, then decreased gradually. Although the total egg output was highest in the 15-19-year age group, individuals with high egg counts were found among all age groups.The prevalence and intensity of infection were higher in men than in women except in the 45-54-year age group. A small proportion (4.1%) of the study population (age range 6-53 years) excreted 50% of the eggs counted in this study. Liver and spleen enlargement were significantly associated with S. japonicum infection in all age groups. The frequency of a past history of dysentery and marked liver enlargement (>/= 5 cm) increased in parallel with increasing egg counts. Clustering of individuals with high egg counts in households was observed, but there was no correlation between geographical proximity of residence to potential transmission sites and household infection rates. An effective control strategy would be based on treatment of all infected persons in this endemic area rather than only a selected age group.
在菲律宾吕宋岛的一个乡村社区，采用新改良的定量厚涂片法和硫柳汞 - 碘 - 甲醛浓缩法（MIFC）进行粪便检查，在755名研究对象中，日本血吸虫感染的总体患病率为49.5%。患病率高峰出现在15 - 19岁年龄组，随后逐渐下降。虽然15 - 19岁年龄组的总产卵量最高，但所有年龄组中均发现有高卵计数的个体。除45 - 54岁年龄组外，男性的感染率和感染强度高于女性。研究人群（年龄范围6 - 53岁）中一小部分（4.1%）排出了本研究中所计数虫卵的50%。在所有年龄组中，肝脾肿大均与日本血吸虫感染显著相关。痢疾既往史和明显肝肿大（≥5 cm）的频率随卵计数增加而平行上升。观察到高卵计数个体在家庭中的聚集现象，但居住地点与潜在传播地点的地理距离与家庭感染率之间没有相关性。有效的控制策略应基于对该流行地区所有感染者进行治疗，而不是仅对选定的年龄组进行治疗。
