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重度大麻吸食者红细胞中2,3-二磷酸甘油酸(2,3 DPG)和三磷酸腺苷(ATP)的水平。

Levels of erythrocyte 2,3 DPG and ATP in heavy hashish smokers.

作者信息

Kalofoutis A, Koutselinis A, Lekakis J, Miras C

出版信息

Experientia. 1980 Aug 15;36(8):897-8. doi: 10.1007/BF01953779.

DOI:10.1007/BF01953779
PMID:6969187
Abstract

The variations in concentration of ATP and 2,3 DPG, and in lactic acid production as a function of time, were measured in the erythrocytes of heavy smokers. Results indicate that the most remarkable reduction in concentration of the compounds examined occurred at 30 and 45 min after hashish smoking. The findings are discussed in connection with the possible influence of hashish components, especially delta 9-THC, on the erythrocyte glycolytic pathway.

摘要

对重度吸烟者红细胞中ATP和2,3 -二磷酸甘油酸(2,3 DPG)的浓度变化以及乳酸生成随时间的变化进行了测量。结果表明,所检测化合物浓度最显著的降低发生在吸食大麻后30分钟和45分钟。结合大麻成分尤其是Δ9 - 四氢大麻酚(delta 9-THC)对红细胞糖酵解途径的可能影响对这些发现进行了讨论。

相似文献

1
Levels of erythrocyte 2,3 DPG and ATP in heavy hashish smokers.重度大麻吸食者红细胞中2,3-二磷酸甘油酸(2,3 DPG)和三磷酸腺苷(ATP)的水平。
Experientia. 1980 Aug 15;36(8):897-8. doi: 10.1007/BF01953779.
2
Regeneration of 2,3-bisphosphoglycerate and ATP of stored erythrocytes by phosphoenolpyruvate; a new preservative for blood storage.磷酸烯醇丙酮酸对储存红细胞2,3-二磷酸甘油酸和三磷酸腺苷的再生作用;一种新的血液保存剂。
Prog Clin Biol Res. 1981;55:577-94.
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Erythrocyte adenosine triphosphate and 2,3-diphosphoglycerate after human renal transplantation: dissociation from hypophosphataemia.
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Hematocrit and hemoglobin, ATP and DPG concentrations in Andean man: the interaction of altitude and trace metals with glycolytic and hematologic parameters in man.
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In vivo red cell glycolytic control and DPG-ATP levels.体内红细胞糖酵解控制及二磷酸甘油酸-三磷酸腺苷水平
Ann N Y Acad Sci. 1974 Nov 29;241(0):513-23. doi: 10.1111/j.1749-6632.1974.tb21907.x.
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[Theoretical studies on the influence of binding constants of hemoglobin for ATP and 2,3-diphosphoglycerate on erythrocyte glycolysis].[血红蛋白对ATP和2,3-二磷酸甘油酸结合常数对红细胞糖酵解影响的理论研究]
Acta Biol Med Ger. 1978;37(7):979-92.
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[Method for the simultaneous determination of 2,3-DPG and ATP in erythrocytes].[红细胞中2,3 - 二磷酸甘油酸和三磷酸腺苷的同步测定方法]
Lab Delo. 1980(7):424-6.

本文引用的文献

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The effect of marijuana on carbohydrate metabolism.大麻对碳水化合物代谢的影响。
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Changes induced by hashish constituents on human erythrocyte phospholipids.大麻成分对人红细胞磷脂的影响。
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The problem of tissue oxygenation in diabetes mellitus. I. Its relation to the early functional changes in the microcirculation of diabetic subjects.糖尿病中的组织氧合问题。I. 其与糖尿病患者微循环早期功能变化的关系。
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