Krajina Z, Kosoković F, Bolanca S, Bumber Z
Laryngol Rhinol Otol (Stuttg). 1980 Jun;59(6):341-3.
The relationship between surgery, chemotherapy, irradiation and the immunological state in patients of laryngeal cancer with or without metastasis was investigated. The lymphocyte reaction to PHA (Phytohaemagglutinin) stimulation and T-lymphocyte count was examined before and immediately after the therapy in 66 patients divided into three groups. From the results the authors conclude that surgical treatment (partial or total laryngectomy, with or without radical Neckdissection influence the immunological state of the patients at least, chemotherapy more and irradiation at most.
研究了有或无转移的喉癌患者手术、化疗、放疗与免疫状态之间的关系。将66例患者分为三组，在治疗前和治疗后立即检测其对PHA（植物血凝素）刺激的淋巴细胞反应和T淋巴细胞计数。根据结果，作者得出结论：手术治疗（部分或全喉切除术，有或无根治性颈清扫术）至少会影响患者的免疫状态，化疗影响更大，放疗影响最大。
