Curry F E
Am J Physiol. 1981 Jan;240(1):H29-32. doi: 10.1152/ajpheart.1981.240.1.H29.
Paired determinations of the hydraulic conductivity (Lv) of individually perfused capillaries in frog mesentery were measured at 22-25 and 5-8 degrees C. The mean value of the ratio of the hydraulic conductivity at 22-25 to that at 5-8 degrees C was 1.76 +/- 0.22 (SE) in 10 capillaries perfused with albumin in the Ringer perfusate and 1.81 +/- 0.11 in six capillaries perfused with Ringer alone. The ratio of Lp can be accounted for in terms of a 1.60-fold increase in water viscosity between 22-25 and 5-8 degrees C. The results conform to the hypothesis that the structure of the principal pathway for water across the capillary wall is invariant with temperature; models of the water pathway that imply a change in the number of pathways or a change in pathway structure with temperature are incompatible with these results. Temperature gradients across the tissue are negligible in these experiments; calculations show that in the presence of temperature gradients, which occur during tissue cooling or rewarming, transcapillary water flows due to thermoosmosis are likely to occur.
在22 - 25摄氏度和5 - 8摄氏度下，对蛙肠系膜中单个灌注毛细血管的水力传导率（Lv）进行了配对测定。在林格氏灌注液中灌注白蛋白的10根毛细血管中，22 - 25摄氏度时的水力传导率与5 - 8摄氏度时的水力传导率之比的平均值为1.76±0.22（标准误），而在仅灌注林格氏液的6根毛细血管中该比值为1.81±0.11。Lp的比值可以用22 - 25摄氏度到5 - 8摄氏度之间水粘度增加1.60倍来解释。结果符合这样的假设，即水穿过毛细血管壁的主要途径的结构不随温度变化；暗示途径数量变化或途径结构随温度变化的水途径模型与这些结果不相符。在这些实验中，组织上的温度梯度可忽略不计；计算表明，在组织冷却或复温过程中出现温度梯度时，由于热渗透可能会发生跨毛细血管的水流。
