Holman J M, Rikkers L F
Am J Surg. 1980 Dec;140(6):816-20. doi: 10.1016/0002-9610(80)90124-5.
Peripheral intravenous Pitressin infusion, use of the Sengstaken-Blakemore tube, or both effectively controlled variceal hemorrhage in 69 percent of patients, allowing an interval of medical management before elective portasystemic shunt surgery. Prolonged preoperative in-hospital management significantly improved hepatic function in initially poor risk patients. This improvement in hepatic function appeared to result in decreased postoperative morbidity and an operative mortality equal to that of good risk patients.
外周静脉输注垂体后叶素、使用Sengstaken - Blakemore管或两者联合使用可有效控制69%患者的静脉曲张出血,从而在择期门体分流手术前有一段间隔进行内科治疗。对初始风险较高的患者进行长时间的术前住院治疗可显著改善肝功能。肝功能的这种改善似乎使术后发病率降低,手术死亡率与风险较低的患者相当。