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急性静脉曲张出血的外科治疗

Surgical management of acute variceal hemorrhage.

作者信息

Rikkers L F, Jin G

机构信息

Department of Surgery, University of Nebraska Medical Center, Omaha 68198-3280.

出版信息

World J Surg. 1994 Mar-Apr;18(2):193-9. doi: 10.1007/BF00294400.

Abstract

The advent of more effective nonoperative therapies, mainly endoscopic variceal sclerosis, has decreased the need for emergency surgery for control of acute variceal hemorrhage. In centers where it is available, nonoperative portal decompression by transjugular intrahepatic portosystemic shunting (TIPS) is likely to have a further impact. When acute or chronic sclerotherapy fails or when bleeding is secondary to gastric varices or portal hypertensive gastropathy, emergency surgery may be life-saving and should be done promptly before worsening hepatic functional decompensation develops. Child's class C liver disease is not a contraindication to emergency surgery; many patients who fail nonoperative attempts at control of bleeding are of this risk status. The most commonly utilized emergency procedures are portacaval and interposition mesocaval shunts, both of which are effective, and esophageal transection, which is associated with a higher incidence of late rebleeding. An emergency distal splenorenal shunt is appropriate for selected patients who are not actively bleeding at the time of surgery. TIPS is the preferred alternative for acute or chronic endoscopic sclerotherapy failures who are candidates for liver transplantation within the succeeding 6 to 12 months.

摘要

更有效的非手术治疗方法的出现,主要是内镜下静脉曲张硬化疗法,减少了控制急性静脉曲张出血所需的急诊手术。在有经颈静脉肝内门体分流术(TIPS)的中心,这种非手术门体减压方法可能会产生进一步影响。当急性或慢性硬化疗法失败,或者出血继发于胃静脉曲张或门脉高压性胃病时,急诊手术可能挽救生命,应在肝功能失代偿恶化之前迅速进行。Child C级肝病并非急诊手术的禁忌证;许多非手术控制出血尝试失败的患者都处于这种风险状态。最常用的急诊手术是门腔分流术和间置式肠系膜上腔静脉分流术,两者都有效,还有食管横断术,但其晚期再出血发生率较高。急诊远端脾肾分流术适用于手术时未发生活动性出血的特定患者。对于在接下来6至12个月内有肝移植指征、急性或慢性内镜硬化疗法失败的患者,TIPS是首选的替代治疗方法。

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