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In vivo rates of pyrimidine nucleotide metabolism in intact mouse T-lymphoma (s-49) cells treated with 5-fluorouracil.

作者信息

Maybaum J, Cohen M B, Sadee W

出版信息

J Biol Chem. 1981 Mar 10;256(5):2126-30.

PMID:6970198
Abstract
摘要

相似文献

1
In vivo rates of pyrimidine nucleotide metabolism in intact mouse T-lymphoma (s-49) cells treated with 5-fluorouracil.用5-氟尿嘧啶处理的完整小鼠T淋巴瘤(S-49)细胞中嘧啶核苷酸代谢的体内速率。
J Biol Chem. 1981 Mar 10;256(5):2126-30.
2
Regulation of RNA- and DNA-directed actions of 5-fluoropyrimidines in mouse T-lymphoma (S-49) cells.5-氟嘧啶在小鼠T淋巴瘤(S-49)细胞中对RNA和DNA定向作用的调控
Cancer Res. 1980 Nov;40(11):4209-15.
3
Biochemical aspects of chemotherapy of mouse colon carcinoma: fluoropyrimidines and pyrazofurin.
Cancer. 1977 Nov;40(5 Suppl):2681-91. doi: 10.1002/1097-0142(197711)40:5+<2681::aid-cncr2820400941>3.0.co;2-e.
4
Kinetics of N-(phosphonacetyl)-L-aspartate and pyrazofurin depletion of pyrimidine ribonucleotide and deoxyribonucleotide pools and their relationship to nucleic acid synthesis in intact and permeabilized cells.N-(膦酰乙酰基)-L-天冬氨酸和吡唑呋林对完整细胞和通透细胞中嘧啶核糖核苷酸池和脱氧核糖核苷酸池的消耗动力学及其与核酸合成的关系。
Cancer Res. 1982 Nov;42(11):4525-31.
5
Changes in the deoxyribonucleoside triphosphate pools of mouse 5178Y lymphoma cells following exposure to methotrexate or 5-fluorouracil.暴露于甲氨蝶呤或5-氟尿嘧啶后小鼠5178Y淋巴瘤细胞中脱氧核糖核苷三磷酸库的变化。
Cancer Res. 1973 Dec;33(12):3086-90.
6
Metabolism of UDP-N-acetyl-hexoses and UDP-hexoses in normal human T-lymphocytes and MOLT-3 T-leukemia cells.
Adv Exp Med Biol. 1994;370:265-8. doi: 10.1007/978-1-4615-2584-4_56.
7
Changes in the pyrimidine deoxynucleoside triphosphate pools of L5178Y cells after their exposure to methotrexate and 5-fluorouracil.L5178Y细胞暴露于甲氨蝶呤和5-氟尿嘧啶后嘧啶脱氧核苷三磷酸池的变化。
Biochem J. 1972 Sep;129(3):48P-49P. doi: 10.1042/bj1290048pb.
8
Intracellular purine and pyrimidine nucleotide pools of human T and B lymphocytes.人类T淋巴细胞和B淋巴细胞的细胞内嘌呤和嘧啶核苷酸库。
Adv Exp Med Biol. 1986;195 Pt A:567-73. doi: 10.1007/978-1-4684-5104-7_95.
9
[Search for biochemical criteria of sensitivity and resistance of tumor cells to antimetabolites].
Vestn Akad Med Nauk SSSR. 1978(5):58-64.
10
Deoxyribonucleoside triphosphate metabolism and the mammalian cell cycle. Effects of hydroxyurea on mutant and wild-type mouse S49 T-lymphoma cells.脱氧核糖核苷三磷酸代谢与哺乳动物细胞周期。羟基脲对突变型和野生型小鼠S49 T淋巴瘤细胞的影响。
Exp Cell Res. 1987 Jan;168(1):79-88. doi: 10.1016/0014-4827(87)90417-4.

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Variation of mutation and recombination frequencies over a range of thymidylate concentrations in a diploid thymidylate auxotroph.在二倍体胸腺嘧啶营养缺陷型中,嘧啶核苷酸浓度范围内突变和重组频率的变化。
Curr Genet. 1983 Sep;7(5):399-402. doi: 10.1007/BF00445881.
2
Pemetrexed pharmacokinetics and pharmacodynamics in a phase I/II study of doublet chemotherapy with vinorelbine: implications for further optimisation of pemetrexed schedules.培美曲塞与长春瑞滨联合化疗的I/II期研究中的药代动力学和药效学:对培美曲塞给药方案进一步优化的启示
Br J Cancer. 2007 Oct 22;97(8):1071-6. doi: 10.1038/sj.bjc.6603995. Epub 2007 Oct 2.
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Clinical and preclinical pharmacokinetics of raltitrexed.
雷替曲塞的临床和临床前药代动力学
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Tomudex (ZD1694): from concept to care, a programme in rational drug discovery.拓姆替克(ZD1694):从概念到医疗,合理药物研发项目
Invest New Drugs. 1996;14(3):305-16. doi: 10.1007/BF00194534.
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Cell cycle-dependent effects on deoxyribonucleotide and DNA labeling by nucleoside precursors in mammalian cells.细胞周期对哺乳动物细胞中核苷前体的脱氧核糖核苷酸和DNA标记的依赖性影响。
Mol Cell Biol. 1987 Jan;7(1):532-4. doi: 10.1128/mcb.7.1.532-534.1987.
6
Guanine for DNA synthesis. A compulsory route through ribonucleotide reductase.用于DNA合成的鸟嘌呤。通过核糖核苷酸还原酶的一条必由途径。
Biochem J. 1988 Nov 1;255(3):1045-8. doi: 10.1042/bj2551045.
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Compartmentation of guanine nucleotide precursors for DNA synthesis.用于DNA合成的鸟嘌呤核苷酸前体的区室化。
Biochem J. 1986 Mar 1;234(2):263-9. doi: 10.1042/bj2340263.
8
Mechanisms of 2'-deoxyguanosine toxicity in mouse T-lymphoma cells with purine nucleoside phosphorylase deficiency and resistance to inhibition of ribonucleotide reductase by dGTP.嘌呤核苷磷酸化酶缺乏且对dGTP抑制核糖核苷酸还原酶具有抗性的小鼠T淋巴瘤细胞中2'-脱氧鸟苷毒性的机制
Biochem J. 1990 Jun 15;268(3):725-31. doi: 10.1042/bj2680725.