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血小板上的人类白细胞抗原C抗原

HLA--C antigens on platelets.

作者信息

Mueller-Eckhardt G, Hauck M, Kayser W, Mueller-Eckhardt C

出版信息

Tissue Antigens. 1980 Jul;16(1):91-4.

PMID:6970427
Abstract

The direct demonstration of HLA-C antigens Cw2, Cw-3, and Cw4 on human platelets is described. The antigens were detected by means of a platelet radioimmune anti-IgG test using acid eluates from platelets and lymphocytotoxic antisera. It is concluded that HLA-C determinants are only weakly expressed on platelets. Individual differences observed reflect antigenic variations.

摘要

本文描述了人类血小板上HLA-C抗原Cw2、Cw3和Cw4的直接证明。这些抗原是通过血小板放射免疫抗IgG试验检测的,该试验使用血小板酸洗脱液和淋巴细胞毒性抗血清。得出的结论是,HLA-C决定簇在血小板上仅微弱表达。观察到的个体差异反映了抗原变异。

相似文献

1
HLA--C antigens on platelets.血小板上的人类白细胞抗原C抗原
Tissue Antigens. 1980 Jul;16(1):91-4.
2
[Antileukocyte and antithrombocyte antibodies in correlation with the incidence of cytotoxic anti-HL-A antibodies in hematologic diseases of various etiology].[不同病因血液系统疾病中抗白细胞和抗血小板抗体与细胞毒性抗人白细胞抗原抗体发生率的相关性]
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Hum Immunol. 2007 Jun;68(6):500-6. doi: 10.1016/j.humimm.2007.02.007. Epub 2007 Mar 21.
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Evidence of platelet complement-fixing and lymphocytotoxic anti-A-1 antibodies.血小板补体结合及淋巴细胞毒性抗A-1抗体的证据。
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The use of microfluorochromasia in platelet crossmatching as a means of evaluating thrombocytopenic patient sera.微量荧光染色法在血小板交叉配血中作为评估血小板减少症患者血清的一种手段的应用。
Transplant Proc. 1981 Mar;13(1 Pt 2):995-7.
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The mechanism of platelet aggregation induced by HLA-related antibodies.HLA相关抗体诱导血小板聚集的机制。
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Platelet transfusions are associated with the development of anti-major histocompatibility complex class I antibodies in patients with left ventricular assist support.血小板输注与左心室辅助支持患者抗主要组织相容性复合体I类抗体的产生有关。
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Studies on the platelet radioactive anti-immunoglobulin test.
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[Test for anti-platelet antibody].[抗血小板抗体检测]
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Anti-HLA antibodies with complementary and synergistic interaction geometries promote classical complement activation on platelets.具有互补和协同相互作用几何形状的抗 HLA 抗体可促进血小板上经典补体的激活。
Haematologica. 2019 Feb;104(2):403-416. doi: 10.3324/haematol.2018.201665. Epub 2018 Sep 27.

引用本文的文献

1
Identification of specificities of antibodies against human leukocyte antigens in blood donors.鉴定献血者血液中针对人类白细胞抗原的抗体特异性。
Transfusion. 2010 Aug;50(8):1749-60. doi: 10.1111/j.1537-2995.2010.02589.x. Epub 2010 Feb 11.
2
Detection of HLA class I-specific antibodies by the QuikScreen enzyme-linked immunosorbent assay.采用快速筛查酶联免疫吸附试验检测HLA I类特异性抗体。
Clin Diagn Lab Immunol. 1997 May;4(3):252-7. doi: 10.1128/cdli.4.3.252-257.1997.