对苯佐卡因的光接触性过敏。

Photocontact allergy to benzocaine.

作者信息

Kaidbey K H, Allen H

出版信息

Arch Dermatol. 1981 Feb;117(2):77-9.

Abstract

A photodermatitis developed in two patients after the use of commercial sunscreens and a topical anesthetic lotion containing benzocaine. Photopatch testing indicated the presence of photocontact allergy to benzocaine. One patient had a positive photopatch test to a commercial glyceryl para-aminobenzoic acid (PABA) preparation that was heavily contaminated with benzocaine, but not to a benzocaine-free sample of glyceryl PABA. Benzocaine failed to produce phototoxic reactions in normal volunteers. Efforts to induce photocontact allergy in guinea pigs were unsuccessful.

摘要

两名患者在使用市售防晒霜和一种含苯佐卡因的局部麻醉洗剂后出现了光性皮炎。光斑贴试验表明存在对苯佐卡因的光接触性过敏。一名患者对一种严重污染有苯佐卡因的市售对氨基苯甲酸甘油酯（PABA）制剂光斑贴试验呈阳性，但对不含苯佐卡因的对氨基苯甲酸甘油酯样品呈阴性。苯佐卡因在正常志愿者中未产生光毒性反应。在豚鼠中诱导光接触性过敏的尝试未成功。