Thune P
Photodermatol. 1984 Feb;1(1):5-9.
Patch and photopatch test studies in 23 patients with reactions to sunscreen preparations revealed 17 photopatch and 38 patch test-positive reactions. The offending allergens could be traced in 18 of the 23 patients. Allergy to PABA was demonstrated in 11 patients, 5 of whom had photocontact allergy. Photocontact allergy to oxybenzone was seen in 3 patients, while 8 were sensitive to cinnamates, and 2 of these had a photocontact allergy. Six patients were sensitive to the PABA-derivatives octyldimethyl-PABA and amyldimethyl-PABA and the ester glyceryl PABA, 2 of whom had a photocontact allergy. None of the 3 patients with benzocaine sensitivity, including 2 with a photocontact allergy, reacted to the PABA-ester. Eight patients were sensitive to different cinnamates, including 2 cases of photocontact allergy. In one patient sensitivity to two azo-naphthol dyes, contained in a sunscreen preparation, was confirmed. Five other patients had positive skin test reactions to different sunscreen preparations but the offending allergen could not be traced. Thirteen of the 23 patients had chronic light sensitive disorders such as polymorphic light eruption (PMLE) or persistent light reactivity (PLR). Sunscreen sensitivity appears to be more common than previously reported.
对23例对防晒制剂有反应的患者进行的斑贴试验和光斑贴试验研究显示，有17例光斑贴试验阳性反应和38例斑贴试验阳性反应。在23例患者中的18例中可找到致病过敏原。11例患者证实对对氨基苯甲酸（PABA）过敏，其中5例有光接触性过敏。3例患者出现对二苯甲酰甲烷的光接触性过敏，8例对桂皮酸盐敏感，其中2例有光接触性过敏。6例患者对PABA衍生物辛基二甲基-PABA、戊基二甲基-PABA和对氨基苯甲酸甘油酯敏感，其中2例有光接触性过敏。3例对苯佐卡因敏感的患者（包括2例有光接触性过敏的患者）对PABA酯均无反应。8例患者对不同的桂皮酸盐敏感，包括2例光接触性过敏病例。在1例患者中证实对一种防晒制剂中含有的两种偶氮萘酚染料敏感。其他5例患者对不同的防晒制剂皮肤试验呈阳性反应，但无法找到致病过敏原。23例患者中有13例患有慢性光敏性疾病，如多形性日光疹（PMLE）或持续性光反应性（PLR）。防晒敏感性似乎比以前报道的更为常见。
