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反应性关节炎中滑液和外周血淋巴细胞。病例报告。

Lymphocytes of synovial fluid and peripheral blood in reactive arthritis. A case report.

作者信息

Bjelle A, Tärnvik A

出版信息

Scand J Infect Dis Suppl. 1980;Suppl 24:58-62.

PMID:6970984
Abstract

Lymphocytes were isolated from eight samples of synovial fluid obtained over a period of six weeks from a patient with reactive arthritis after venereal infection of unknown microbial etiology. The percentages of T lymphocytes were consistently higher in synovial fluid than in paired blood samples, whereas those of B lymphocytes were consistently lower in synovial fluid than in blood. When incubated in vitro the spontaneous DNA synthesis of the synovial fluid and blood lymphocytes was low. When phytohaemagglutinin or tuberculin was present in the cultures the lymphocytes from blood as well as those from synovial fluid responded with synthesis of deoxyribonucleic acid and phytohaemagglutinin dose response curves of lymphocytes from the two sources were similar. Thus T lymphocytes of synovial fluid showed a similar in vitro reactivity as those from blood.

摘要

从一名患有反应性关节炎的患者身上,在六周时间内采集了八份滑液样本,该患者因不明微生物病因的性传播感染而患病。滑液中T淋巴细胞的百分比始终高于配对血液样本中的百分比,而B淋巴细胞的百分比在滑液中始终低于血液中的百分比。当在体外培养时,滑液和血液淋巴细胞的自发DNA合成较低。当培养物中存在植物血凝素或结核菌素时,血液中的淋巴细胞以及滑液中的淋巴细胞都会通过合成脱氧核糖核酸做出反应,并且来自这两种来源的淋巴细胞的植物血凝素剂量反应曲线相似。因此,滑液中的T淋巴细胞在体外表现出与血液中的T淋巴细胞相似的反应性。

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Scand J Infect Dis Suppl. 1980;Suppl 24:58-62.
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