未经治疗的妊娠滋养细胞肿瘤中特定胎盘蛋白（人绒毛膜促性腺激素、妊娠特异性β-1糖蛋白和胎盘蛋白5）的循环浓度。
Circulating concentrations of specific placental proteins (human chorionic gonadotropin, pregnancy-specific beta-1 glycoprotein, and placental protein 5) in untreated gestational trophoblastic tumors.
作者信息
Lee J N, Salem H T, Al-Ani A T, Chard T, Huang S C, Ouyang P C, Wei P Y, Seppälä M
出版信息
Am J Obstet Gynecol. 1981 Mar 15;139(6):702-4. doi: 10.1016/0002-9378(81)90490-7.
PMID:6971058
Abstract
Serum levels of human chorionic gonadotropin (hCG), pregnancy-specific beta-1-glycoprotein (SP1), and placental protein 5 (PP5) were measured prior to treatment in 14 patient with hydatidiform mole and in nine patients with choriocarcinoma. Measurement of circulating levels of SP1 and PP5, but not hCG, provides a distinction between benign and malignant gestational trophoblastic tumors.
摘要
在对14例葡萄胎患者和9例绒毛膜癌患者进行治疗前，检测了血清中人绒毛膜促性腺激素（hCG）、妊娠特异性β1-糖蛋白（SP1）和胎盘蛋白5（PP5）的水平。检测循环中的SP1和PP5水平而非hCG水平，可区分良性和恶性妊娠滋养细胞肿瘤。
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