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阴道毛滴虫在上皮细胞培养中的行为及致病性：光镜和扫描电镜研究

Behaviour and pathogenicity of Trichomonas vaginalis in epithelial cell cultures: a study by light and scanning electron microscopy.

作者信息

Heath J P

出版信息

Br J Vener Dis. 1981 Apr;57(2):106-17. doi: 10.1136/sti.57.2.106.

DOI:10.1136/sti.57.2.106
PMID:6971140
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1045885/
Abstract

The behaviour and pathogenic effects of Trichomonas vaginalis in mammalian cell cultures were studied using light microscopy and scanning electron microscopy. Six hours after inoculation of the parasites into the cell cultures about 10% of the epithelial monolayer was destroyed. The parasites adhered to the epithelial cells, developed an amoeboid morphology, and crawled over and under the monolayer of cells. These observations suggest that the adhesiveness, amoeboid morphology, and motility of T vaginalis may be important mechanisms in the injury caused to the vaginal epithelium.

摘要

利用光学显微镜和扫描电子显微镜研究了阴道毛滴虫在哺乳动物细胞培养物中的行为和致病作用。将寄生虫接种到细胞培养物中6小时后，约10%的上皮单层被破坏。寄生虫附着在上皮细胞上，形成阿米巴样形态，并在细胞单层上和下方爬行。这些观察结果表明，阴道毛滴虫的黏附性、阿米巴样形态和运动性可能是对阴道上皮造成损伤的重要机制。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0bbe/1045885/e434a88750f8/brjvendis00020-0035-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0bbe/1045885/5389937cfe0f/brjvendis00020-0026-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0bbe/1045885/017f104acc52/brjvendis00020-0027-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0bbe/1045885/6ba2569929fa/brjvendis00020-0028-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0bbe/1045885/60b23e383acc/brjvendis00020-0029-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0bbe/1045885/46fb066f2ceb/brjvendis00020-0030-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0bbe/1045885/ba60752837e1/brjvendis00020-0031-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0bbe/1045885/8b20ee7f7671/brjvendis00020-0032-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0bbe/1045885/9c57595766bc/brjvendis00020-0033-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0bbe/1045885/ad58078fc357/brjvendis00020-0033-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0bbe/1045885/c4f9f29fcc56/brjvendis00020-0034-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0bbe/1045885/e434a88750f8/brjvendis00020-0035-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0bbe/1045885/5389937cfe0f/brjvendis00020-0026-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0bbe/1045885/017f104acc52/brjvendis00020-0027-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0bbe/1045885/6ba2569929fa/brjvendis00020-0028-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0bbe/1045885/60b23e383acc/brjvendis00020-0029-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0bbe/1045885/46fb066f2ceb/brjvendis00020-0030-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0bbe/1045885/ba60752837e1/brjvendis00020-0031-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0bbe/1045885/8b20ee7f7671/brjvendis00020-0032-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0bbe/1045885/9c57595766bc/brjvendis00020-0033-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0bbe/1045885/ad58078fc357/brjvendis00020-0033-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0bbe/1045885/c4f9f29fcc56/brjvendis00020-0034-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0bbe/1045885/e434a88750f8/brjvendis00020-0035-a.jpg

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Cancer. 1959 Nov-Dec;12:1171-93. doi: 10.1002/1097-0142(195911/12)12:6<1171::aid-cncr2820120613>3.0.co;2-4.
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A study of Trichomonas vaginalis in human cell culture.一项关于阴道毛滴虫在人类细胞培养中的研究。
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Responses of cells to pH changes in the medium.细胞对培养基中pH变化的反应。
阴道毛滴虫提取物及其亚组分的神经鞘磷脂酶活性。
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