Tokunaga M, Sato E
Cancer. 1980 Sep 1;46(5):1231-9. doi: 10.1002/1097-0142(19800901)46:5<1231::aid-cncr2820460525>3.0.co;2-u.
As of March 1978, the prognosis was confirmed in 715 non-Hodgkin's lymphoma cases reported during the 12-year period from 1965 through 1976 in the Prefecture of Kagoshima. Included were 222 cases of extranodal lymphoma. Patients with the initial tumor site in the gastrointestinal tract and Waldeyer's ring had a relatively good probability of survival. Among the patients with cutaneous lymphomas, those with the mycosis fungoides type had a poor survival rate. In Kagoshima Prefecture, the survival curve for cases of nodal lymphomas is characteristically much poorer than those reported in the medical literature. Of the nodal lymphomas, the nodular type was found in 128 cases and the five-year survival rate was 15%, while the diffuse type accounted for 365 cases and the five-year survival rate was 8%. The paracortex type, considered to be of T-cell origin, accounted for 55 cases and the five-year survival rate was 0%. These differences were statistically significant. Based on our data, the classification of nodular lymphomas into subtypes according to the degree of nodularity was found to be useful since it was related to clinical stage and survival. Rappaport's cellular classification of diffuse lymphoma is related to prognosis and was found to be useful, but problems still remain in determining T- and B-cell types by means of cellular morphology and thus further study is warranted.
截至1978年3月，对1965年至1976年这12年间鹿儿岛县报告的715例非霍奇金淋巴瘤病例的预后情况进行了确认。其中包括222例结外淋巴瘤。初始肿瘤部位在胃肠道和瓦尔代尔环的患者存活概率相对较高。在皮肤淋巴瘤患者中，蕈样肉芽肿型患者的存活率较低。在鹿儿岛县，结节性淋巴瘤病例的生存曲线明显比医学文献中报告的情况差。在结节性淋巴瘤中，结节型有128例，五年生存率为15%；弥漫型有365例，五年生存率为8%。被认为起源于T细胞的副皮质型有55例，五年生存率为0%。这些差异具有统计学意义。根据我们的数据，发现根据结节程度将结节性淋巴瘤分为亚型是有用的，因为它与临床分期和生存情况相关。拉帕波特对弥漫性淋巴瘤的细胞分类与预后相关且被证明是有用的，但通过细胞形态学确定T细胞和B细胞类型仍存在问题，因此有必要进一步研究。
