结核性脑膜炎中的脑脊液细胞。体液免疫和细胞免疫反应。
CSF cells in tuberculous meningitis. Humoral and cellular immune response.
作者信息
Pelc S, De Maertelaere E
出版信息
J Neurol Sci. 1981 Feb;49(2):223-8. doi: 10.1016/0022-510x(81)90080-0.
PMID:6971324
Abstract
In 10 patients with tuberculous meningitis both T and B lymphocyte activation was observed in the CSF from clinical onset of disease. During the course of the illness, the humoral response remained most marked, disappearing by 2 months, while the cellular immune response continued for about another 3 months. This contrasts with acute viral meningitis, in which both responses cease within 1-2 weeks of disease.
摘要
在10例结核性脑膜炎患者中，从疾病临床发作起，脑脊液中就观察到T淋巴细胞和B淋巴细胞的激活。在病程中，体液反应一直最为显著，在2个月时消失，而细胞免疫反应则持续约3个月。这与急性病毒性脑膜炎形成对比，在急性病毒性脑膜炎中，两种反应在发病后1 - 2周内就会停止。
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