Mattsson J L, Fry W N, Boward C A, Miller E
Am J Vet Res. 1978 Aug;39(8):1279-81.
As a prelude to neurobehavioral toxicologic studies in neonatal minipigs, normal maturational changes in the visual evoked response (VER) were determined in 6 Hormel-bred minipigs. The VER were highly variable for the 1st several days of life, but were reasonably stable by the 2nd weeks. All adult waveform components were present at birth, and maturational changes primarily affected waveform latency and consistency. Only one waveform (Pi) was sufficiently distinct and consistent for statistical evaluation. At birth the latency to Pi was about 102 ms. The latency of Pi rapidly decreased to about 56 ms during the next 25 days, and subsequent changes were minimal. Comparison with other species indicates many cross-species relationships of specific VER components, with the minipig VER having many maturational and topographic similarities to the human VER.
作为对新生小型猪进行神经行为毒理学研究的前奏，在6只荷美尔培育的小型猪中测定了视觉诱发电位（VER）的正常成熟变化。在出生后的头几天，VER变化很大，但到第二周时就相当稳定了。所有成年波形成分在出生时就已存在，成熟变化主要影响波形潜伏期和一致性。只有一个波形（Pi）足够清晰和一致，可以进行统计评估。出生时Pi波的潜伏期约为102毫秒。在接下来的25天内，Pi波的潜伏期迅速降至约56毫秒，随后变化很小。与其他物种的比较表明，特定VER成分存在许多跨物种关系，小型猪的VER在成熟和地形图方面与人类VER有许多相似之处。
