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[妊娠与免疫系统。I. 妊娠晚期单核细胞的免疫学特征(作者译)]

[Pregnancy and immune system. I. Immunological characterization of mononuclear cells during late pregnancy (author's transl)].

作者信息

Heidenreich W, Peter H H, Deinhardt J, Börner P, Dyllick H, Burkert W, Deicher H

出版信息

Geburtshilfe Frauenheilkd. 1981 Feb;41(2):93-5. doi: 10.1055/s-2008-1036970.

Abstract

Lymphocyte preparations obtained from peripheral blood of 36 healthy pregnancy women during the last 4 weeks of gestation were tested for various cell surface markers (E-, EA- EAC-rosettes, surface Ig positive cells). 29 healthy, non-pregnant age matched women served as controls. The cell surface marker analysis did not show significantly different results in the two groups tested except diminished percentages of EA-rosettes in the pregnancy group. EA-rosettes-forming cells (Fc-receptor positive cells) are known to the effectors of spontaneous and antibody dependent lymphocytotoxicity. Therefore, slightly depressed lymphocytotoxicity may be expected during late pregnancy.

摘要

从36名妊娠最后4周的健康孕妇外周血中获取淋巴细胞制剂,检测其各种细胞表面标志物(E-、EA-、EAC-玫瑰花结、表面免疫球蛋白阳性细胞)。29名年龄匹配的健康非孕妇作为对照。细胞表面标志物分析显示,除妊娠组EA-玫瑰花结百分比降低外,两组检测结果无显著差异。已知EA-玫瑰花结形成细胞(Fc受体阳性细胞)是自发和抗体依赖性淋巴细胞毒性的效应细胞。因此,妊娠晚期可能预期淋巴细胞毒性略有降低。

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