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The acute management of intrathecal methotrexate overdose: pharmacologic rationale and guidelines.

作者信息

Addiego J E, Ridgway D, Bleyer W A

出版信息

J Pediatr. 1981 May;98(5):825-8. doi: 10.1016/s0022-3476(81)80859-1.

DOI:10.1016/s0022-3476(81)80859-1
PMID:6971923
Abstract
摘要

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The acute management of intrathecal methotrexate overdose: pharmacologic rationale and guidelines.鞘内注射甲氨蝶呤过量的急性处理：药理学原理与指南
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Absence of neurotoxicity following massive intrathecal administration of methotrexate. Case report.大剂量鞘内注射甲氨蝶呤后无神经毒性。病例报告。
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Intrathecal methotrexate overdose without neurotoxicity: case report and literature review.鞘内注射甲氨蝶呤过量但无神经毒性：病例报告及文献综述
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Methotrexate in the plasma and cerebrospinal fluid of children treated with intermediate dose methotrexate.接受中等剂量甲氨蝶呤治疗的儿童血浆和脑脊液中的甲氨蝶呤
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[High dose methotrexate with citrovorum factor rescue therapy. (2) Measurement of methotrexate and its major metabolite, 7-hydroxymethotrexate in cerebrospinal fluid by high pressure liquid chromatography].[大剂量甲氨蝶呤联合亚叶酸钙解救疗法。（2）用高压液相色谱法测定脑脊液中甲氨蝶呤及其主要代谢物7-羟基甲氨蝶呤]
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[Intrathecal methotrexate--overdosing in pediatric lymphoblastic leukemia].
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Brain damage after intrathecal methotrexate.鞘内注射甲氨蝶呤后的脑损伤
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Accidental High-dose Intrathecal Treatment: Late Results of a Patient.
意外鞘内高剂量治疗：一名患者的晚期结果
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Pharmacokinetics following intraventricular administration of chemotherapy in patients with neoplastic meningitis.肿瘤性脑膜炎患者脑室内给予化疗后的药代动力学。
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Intrathecal chemotherapy with antineoplastic agents in children.儿童鞘内注射抗肿瘤药物化疗
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