Servít Z, Kristof M, Strejcková A
Epilepsia. 1981 Jun;22(3):321-9. doi: 10.1111/j.1528-1157.1981.tb04116.x.
In experiments on animals, airflow through the nasal cavity elicits rhythmic synchronized activity that can trigger and/or elicit epileptic electrographic activities in the limbic structures of the brain. This could be demonstrated in studies of lower vertebrates (frogs and turtles). In the turtle the elicited paroxysmal activity often had the shape of regular high-voltage activity in the theta-frequency range (average frequency, 4.1 Hz). It was further proven in clinical experiments that nasal deep breathing with a closed mouth effectively activates epileptic electrographic phenomena of a temporal (limbic) origin. The activating effect was more pronounced on the side ipsilateral to the ventilated nasal meatus. It could also be evoked by air insufflation into the nasal cavity. This effect was suppressed by anesthesia of the mucous membrane in the upper nasal meatus. Possible mechanisms of this, probably reflex, phenomenon are discussed.
在动物实验中，鼻腔内的气流会引发有节奏的同步活动，这种活动可触发和/或引发大脑边缘结构中的癫痫性电活动。这在对低等脊椎动物（青蛙和乌龟）的研究中得到了证实。在乌龟身上，诱发的阵发性活动通常呈θ频率范围内规则的高电压活动形式（平均频率为4.1赫兹）。临床实验进一步证明，闭嘴进行鼻腔深呼吸可有效激活颞叶（边缘系统）起源的癫痫性电现象。这种激活作用在通气鼻道同侧更为明显。向鼻腔内吹气也可诱发这种效应。上鼻道黏膜麻醉可抑制这种效应。文中讨论了这种可能是反射性现象的潜在机制。
