Skinner M A, Marbrook J
J Immunol Methods. 1981;42(2):171-7. doi: 10.1016/0022-1759(81)90146-0.
Hybridoma cells secreting antibody against heterologous erythrocytes have been used as targets to measure cytotoxic T cell activity. The ability of the target cells to form hemolytic plaques has been used as an index of target viability. It has been possible to devise a sensitive plaque reduction method for measuring cytotoxicity which lends itself to screening small numbers of cytotoxic cells.
分泌抗异源红细胞抗体的杂交瘤细胞已被用作测量细胞毒性T细胞活性的靶标。靶细胞形成溶血斑的能力已被用作靶标活力的指标。已经有可能设计出一种灵敏的噬斑减少法来测量细胞毒性，这种方法适用于筛选少量的细胞毒性细胞。
