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青蛙压缩去皮肌纤维中力产生的抑制作用。

Inhibition of force production in compressed skinned muscle fibers of the frog.

作者信息

Maughan D W, Godt R E

出版信息

Pflugers Arch. 1981 May;390(2):161-3. doi: 10.1007/BF00590200.

DOI:10.1007/BF00590200
PMID:6972521
Abstract

Calcium-activated force development in skinned frog muscle fibers is inhibited by osmotically compressing the fiber, probably owing to a decrease in spacing between the myofilaments. This inhibition depends upon sarcomere length in that fibers at long lengths must be compressed further than those at short lengths to achieve the same degree of inhibition. As a result, this length dependency of inhibition tends to compensate for the reduction of force due solely to the decrease in interfilament spacing which occurs with stretch in intact fibers.

摘要

通过对皮肤完整的青蛙肌肉纤维进行渗透压压缩,可抑制其钙激活的力产生,这可能是由于肌丝间距减小所致。这种抑制作用取决于肌节长度,即长肌节的纤维必须比短肌节的纤维压缩得更多,才能达到相同程度的抑制。因此,这种抑制作用的长度依赖性倾向于补偿仅因完整纤维拉伸时肌丝间距减小而导致的力的降低。

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Myofilament-generated tension oscillations during partial calcium activation and activation dependence of the sarcomere length-tension relation of skinned cardiac cells.在部分钙激活过程中肌丝产生的张力振荡以及去皮肤心肌细胞肌节长度-张力关系的激活依赖性。
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