Crawford E S, Saleh S A
Ann Surg. 1981 Aug;194(2):180-8. doi: 10.1097/00000658-198108000-00012.
The results of graft replacement for aneurysms involving the entire transverse aortic arch have lagged far behind that achieved for similar lesions located elsewhere. For example, prior to the study reported here, the mortality rate of the former, in our experience, was 25%, whereas it was only 8% for the most extensive forms of thoracoabdominal aortic aneurysms. The difference had been due to limitations and complications of methods employed for cerebral and myocardial protection. The high mortality rate in our patients was due to the deficiencies of temporary bypass graft and cardiopulmonary bypass, and separate brachiocephalic perfusion employed for this purpose. This report is concerned with the use of profound hypothermia for cerebral protection and the application of graft inclusion and direct brachiocephalic arterial reattachment to prevent bleeding in region of operation, as so successfully employed in patients with thoracoabdominal aortic aneurysms. The entire thoracic aorta was involved in four patients, the aortic valve in two patients, coronary artery bypass was performed in two patients, and the pulmonary artery was obstructed in one patient. Employing the techniques described in this report, all eight patients with these extensive lesions survived without complication.
累及整个主动脉弓横部的动脉瘤的移植置换结果,远远落后于其他部位类似病变的治疗效果。例如,在本研究报道之前,据我们的经验,前者的死亡率为25%,而最广泛类型的胸腹主动脉瘤的死亡率仅为8%。这种差异是由于用于脑和心肌保护的方法存在局限性和并发症。我们患者的高死亡率是由于临时搭桥移植和体外循环的不足,以及为此采用的单独头臂灌注。本报告关注的是采用深度低温进行脑保护,以及应用移植物包埋和直接头臂动脉再附着以防止手术区域出血,这在胸腹主动脉瘤患者中应用得非常成功。4例患者累及整个胸主动脉,2例患者累及主动脉瓣,2例患者进行了冠状动脉搭桥,1例患者肺动脉受阻。采用本报告中描述的技术,所有这8例患有这些广泛病变的患者均存活且无并发症。