Crawford E S, Crawford J L, Stowe C L, Safi H J
Ann Surg. 1984 Mar;199(3):358-62. doi: 10.1097/00000658-198403000-00018.
Total aortic replacement including aortic valve was performed successfully in the two patients in whom this method of treatment was utilized to correct a chronic dissecting aortic aneurysm. Both patients had moderately severe aortic insufficiency producing increasing heart strain and progressive enlargement of the false lumen of aortic dissection involving the entire aorta despite ideal blood pressure control. In addition, one patient had Marfan's syndrome. The surgical treatment for both patients was performed in two stages. At the first operation, cardiopulmonary bypass, profound hypothermia, and circulatory arrest were employed while the aortic valve and the ascending and transverse aortic arch were replaced and the coronary and brachiocephalic vessels were reattached to the composite valve-graft used for replacement. At the second operation, the entire descending thoracic and abdominal aortic segments were replaced with a graft and the intercostal, lumbar, and visceral arteries reattached thereto. Left vocal cord paralysis occurred in both patients and transient mild paraparesis occurred in only one. Both patients are alive and well, one at 13 months and one at 6 weeks. This experience suggests an additional treatment modality for selected patients with complications of chronic aortic dissection.
在这两名采用该治疗方法纠正慢性主动脉夹层动脉瘤的患者中,成功实施了包括主动脉瓣置换在内的全主动脉置换术。两名患者均有中度严重的主动脉瓣关闭不全,尽管血压控制理想,但仍导致心脏负荷增加,主动脉夹层假腔逐渐扩大累及整个主动脉。此外,其中一名患者患有马凡综合征。两名患者的手术治疗均分两期进行。在第一次手术中,采用体外循环、深度低温和循环阻断,同时置换主动脉瓣、升主动脉和横行主动脉弓,并将冠状动脉和头臂血管重新连接到用于置换的复合瓣膜移植物上。在第二次手术中,用移植物置换整个降胸段和腹主动脉段,并将肋间动脉、腰动脉和内脏动脉重新连接到该移植物上。两名患者均出现左侧声带麻痹,仅一名患者出现短暂性轻度截瘫。两名患者均存活良好,一名随访13个月,一名随访6周。这一经验为部分慢性主动脉夹层并发症患者提示了一种额外的治疗方式。