自我与非自我的区分。
Discrimination between self and nonself.
作者信息
Miller R G
出版信息
Can Med Assoc J. 1980 Aug 23;123(4):272-4.
Abstract
An hypothesis is presented that relates the ability of the immune system to distinguish between "self" and "nonself", the generation of diverse lymphocyte receptors and the role of the major histocompatibility complex. Experimental evidence supporting this hypothesis includes the recent discovery of a cell in the thymus that appears to inactivate thymus-derived lymphocytes reactive against self histocompatibility antigens.
摘要
提出了一种假说，该假说涉及免疫系统区分“自身”和“非自身”的能力、多样淋巴细胞受体的产生以及主要组织相容性复合体的作用。支持这一假说的实验证据包括最近在胸腺中发现的一种细胞，该细胞似乎会使对自身组织相容性抗原产生反应的胸腺来源淋巴细胞失活。
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