Cranin A N, Rockman R
J Am Dent Assoc. 1981 Sep;103(3):412-6. doi: 10.14219/jada.archive.1981.0342.
Histiocytosis X, a term comprising three well-known disease complexes, may have dental mobility as a prodromal or major symptom. In each of three patients described, an oral finding predated the other symptoms. The earliest symptom in one patient was loosened teeth; in another, periodontosis-like symptoms were documented ten years before the patient's report of pelvic pain which led to a diagnosis of eosinophilic granuloma; in the third patient, premature eruption of the primary teeth the gingival bleeding was the prodromal symptom. The clinician should understand the significance of each finding and investigate them until a confirmatory diagnosis is made.
组织细胞增多症X，这一术语涵盖三种知名的疾病复合体，可能以牙齿松动作为前驱症状或主要症状。在所描述的三位患者中，每位患者的口腔表现都先于其他症状出现。一位患者最早的症状是牙齿松动；另一位患者，在报告骨盆疼痛并最终诊断为嗜酸性肉芽肿的十年前就记录到了类似牙周病的症状；第三位患者，乳牙过早萌出和牙龈出血是前驱症状。临床医生应了解每项表现的意义，并对其进行调查，直至做出确诊。
