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心肌温度测绘。改善术中心肌保护。

Myocardial temperature mapping. Improved intraoperative myocardial preservation.

作者信息

Daggett W M, Jacocks M A, Coleman W S, Johnson R G, Lowenstein E, vander Salm T J

出版信息

J Thorac Cardiovasc Surg. 1981 Dec;82(6):883-8.

PMID:6975406
Abstract

An improved approach to intraoperative myocardial preservation technique to ensure uniform myocardial cooling past critically stenosed arteries was developed for patients undergoing aorta-coronary bypass grafting. Proximal anastomoses are done and then, after institution of cardiopulmonary bypass, a separate roller pump head is used to administer a specific controlled volume of cardioplegic solution (1 L) through a 4 degrees C coil to provide controlled pressure in the root of the cross-clamped aorta. Midmyocardial wall temperatures in the anterior, posterolateral, inferior, and septal walls of the left ventricle are measured. Distal anastomoses are then performed sequentially, beginning with the warmest region. After each distal anastomosis, 400 ml of cardioplegic solution are again administered into the aortic root. This approach has been used in 100 consecutive patients from July, 1979, through July 1980 (Group I). and these patients were compared to 97 consecutive patients undergoing aorta-coronary bypass grafting in the previous year (July, 1978, through June, 1979) (Group II) who had myocardial preservation with potassium cardioplegia administered by syringe injection and without regional temperature mapping. There were no perioperative myocardial infarctions in Group I: there were five (5.2%) in Group II (p less than 0.05). A significant reduction in cardiac deaths was also achieved, with two (2.0%) such deaths in Group I and eight (8.2%) in Group II (p less than 0.05). The data suggest that delivery of adequate volumes of cardioplegia solutions by a pressure-regulated system, in combination with myocardial temperature mapping to determine the sequence of bypass grafting, can improve myocardial preservation.

摘要

为接受主动脉 - 冠状动脉搭桥术的患者开发了一种改进的术中心肌保护技术方法,以确保在严重狭窄的动脉处实现均匀的心肌降温。先进行近端吻合,然后在建立体外循环后,使用一个单独的滚压泵头通过一个4℃的盘管输送特定控制体积(1升)的心脏停搏液,以在夹闭主动脉根部提供可控压力。测量左心室前壁、后外侧壁、下壁和间隔壁的心肌中层温度。然后从最温暖的区域开始依次进行远端吻合。每次远端吻合后,再次向主动脉根部注入400毫升心脏停搏液。从1979年7月至1980年7月,这种方法已连续应用于100例患者(第一组)。并将这些患者与上一年(1978年7月至1979年6月)连续接受主动脉 - 冠状动脉搭桥术的97例患者(第二组)进行比较,第二组患者采用注射器注射钾停搏液进行心肌保护且未进行区域温度测绘。第一组围手术期无心肌梗死发生;第二组有5例(5.2%)(p<0.05)。心脏死亡也显著减少,第一组有2例(2.0%),第二组有8例(8.2%)(p<0.05)。数据表明,通过压力调节系统输送足够量的心脏停搏液,并结合心肌温度测绘来确定搭桥顺序,可以改善心肌保护。

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