Francini Fabio, Maresca Marco, Procacci Paolo, Zoppi Massimo
Cattedra di Fisiologia Generale, Servizio di Algologia, University of Florence, I-50134 Florence Italy Cattedra di Terapia Medica Sistematica, Servizio di Algologia, University of Florence, I-50134 Florence Italy.
Pain. 1981 Aug;11(1):49-63. doi: 10.1016/0304-3959(81)90138-X.
In healthy subjects and in subjects with chronic myofascial pain of one lower limb, the following was measured in both lower limbs: (i) sequential Hoffman (H) reflex, (ii) sequential Achilles tendon (T) reflex, (iii) cutaneous pain threshold determined with electrical stimuli, before, during and after transcutaneous electrical nerve stimulation (TENS). In healthy subjects no significant differences were observed between the pain thresholds of the two limbs. During and after TENS, changes of the reflexes were related to the pain thresholds. In the pathological subjects a significant difference of pain threshold was present between the affected limb and the contralateral one. An important difference between healthy and pathological subjects is not the quality but the quantity of the changes induced by TENS, in the sense that the levels of inhibition and facilitation of the reflexes are more evident in patients with pain. Indeed, TENS induces a reset of sensory and of motor system and a parallel long lasting effect both on sensory and on muscular function, with concomitant pain relief in the pathological subjects.
在健康受试者和患有单侧下肢慢性肌筋膜疼痛的受试者中，对双下肢进行了以下测量：(i) 连续霍夫曼（H）反射，(ii) 连续跟腱（T）反射，(iii) 在经皮电神经刺激（TENS）之前、期间和之后，用电刺激测定皮肤痛阈。在健康受试者中，两下肢的痛阈未观察到显著差异。在TENS期间和之后，反射的变化与痛阈相关。在病理受试者中，患侧肢体与对侧肢体之间存在痛阈的显著差异。健康受试者与病理受试者之间的一个重要差异不是变化的性质，而是TENS引起的变化的量，从这个意义上说，反射的抑制和易化水平在疼痛患者中更明显。事实上，TENS会引起感觉和运动系统的重置，以及对感觉和肌肉功能的平行持久影响，同时使病理受试者的疼痛减轻。
