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支气管分泌过多、慢性气流受限和消化性溃疡。

Bronchial hypersecretion, chronic airflow limitation, and peptic ulcer.

作者信息

Kauffmann F, Brille D

出版信息

Am Rev Respir Dis. 1981 Nov;124(5):646-9. doi: 10.1164/arrd.1981.124.5.646.

DOI:10.1164/arrd.1981.124.5.646
PMID:6975591
Abstract

Men with and men without a history of peptic ulcers were compared using respiratory symptoms and spirographic measurements taken from data recorded in an epidemiologic study. Among the 1,049 men examined, 7% reported a history of peptic ulcer. A clear relationship appeared between bronchial hypersecretion and peptic ulcers. It persisted after adjustment for age, smoking habits, social class, and country of origin. Men with ulcers inhaled tobacco smoke more often. Ulcers, smoking, and chronic phlegm were independently related to a lower body build index. It seems that the relationship between smoking and ulcers was greater among men with chronic phlegm, and it is postulated that peptic ulcers and "chronic bronchitis" might be related to a "common secretory disorder." After adjustment for age, men with a history of peptic ulcers had, not a lower FEV1, but a higher vital capacity. A slightly lower FEV1/VC ratio cannot in such cases be considered as an index of chronic airflow limitation.

摘要

在一项流行病学研究中,对有消化性溃疡病史的男性和无消化性溃疡病史的男性进行了比较,比较内容包括呼吸症状和从记录数据中获取的肺功能仪测量结果。在接受检查的1049名男性中,7%的人报告有消化性溃疡病史。支气管分泌亢进与消化性溃疡之间存在明显的关系。在对年龄、吸烟习惯、社会阶层和原籍国进行调整后,这种关系依然存在。有溃疡的男性更常吸入烟草烟雾。溃疡、吸烟和慢性咳痰与较低的身体体型指数独立相关。似乎在有慢性咳痰的男性中,吸烟与溃疡之间的关系更为密切,据推测,消化性溃疡和“慢性支气管炎”可能与一种“共同的分泌紊乱”有关。在对年龄进行调整后,有消化性溃疡病史的男性的第一秒用力呼气容积(FEV1)并非较低,而是肺活量较高。在这种情况下,略低的FEV1/VC比值不能被视为慢性气流受限的指标。

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引用本文的文献

1
Smoking, lung function, and body weight.吸烟、肺功能与体重。
Br Med J (Clin Res Ed). 1983 Apr 16;286(6373):1280. doi: 10.1136/bmj.286.6373.1280-b.