Liquid-chromatographic monitoring of 5-methyltetrahydrofolate in plasma.
作者信息
Giulidori P, Galli-Kienle M, Stramentinoli G
出版信息
Clin Chem. 1981 Dec;27(12):2041-3.
PMID:6975669
Abstract
The liquid-chromatographic measurement of 5-methyltetrahydrofolate in biological fluids is described. The sensitivity of the spectrophotofluorometric detector used allows direct evaluation of basal concentrations of the compound in plasma. Because it is resolved from the other common folates and from methotrexate, the procedure is suitable for monitoring it in plasma of patients receiving high-dose therapy with methotrexate.
摘要
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