内源性交感神经驱动力的减退会降低原发性醛固酮增多症患者的血压。
Withdrawal of endogenous sympathetic drive lowers blood pressure in primary aldosteronism.
作者信息
Nicholls M G, Julius S, Zweifler A J
出版信息
Clin Endocrinol (Oxf). 1981 Sep;15(3):253-8. doi: 10.1111/j.1365-2265.1981.tb00663.x.
We were able to observe the effect of withdrawal of endogenous sympathetic drive in a hypertensive patient with an aldosterone-secreting adrenal adenoma. Acute stimulation of both carotid sinus nerves lowered blood pressure to normotensive or hypotensive levels by reducing peripheral resistance. When chronic carotid sinus nerve stimulation was discontinued, peripheral resistance and blood pressure increased. These data suggest that the sympathetic nervous system is important in the maintenance of hypertension in established primary aldosteronism.
我们得以在一名患有分泌醛固酮的肾上腺腺瘤的高血压患者中观察内源性交感神经驱动撤除的效果。对双侧颈动脉窦神经进行急性刺激，通过降低外周阻力，可使血压降至正常血压或低血压水平。当停止慢性颈动脉窦神经刺激时，外周阻力和血压会升高。这些数据表明，交感神经系统在已确诊的原发性醛固酮增多症患者高血压的维持中起重要作用。
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