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尽管冠状动脉搭桥通畅但心肌再灌注不完全:冠状动脉疾病外科治疗中一个普遍未被认识到的缺点。

Incomplete myocardial reperfusion despite a patent coronary bypass: a generally unrecognized shortcoming of the surgical approach to coronary artery disease.

作者信息

Levin D C, Beckmann C F, Sos T A, Sniderman K

出版信息

Radiology. 1982 Feb;142(2):317-21. doi: 10.1148/radiology.142.2.6976587.

Abstract

When assessing a coronary artery bypass graft, the patency rate is virtually the sole criterion of success. However, this fails to identify grafts which are patent by incompletely reperfuse the diseased vessel. Angiograms of 82 patients with 172 bypassed coronary arteries confirmed patency in 126 (73%); however, in 30 reperfusion was incomplete though the graft was patent, making the rate of complete reperfusion only 56% (96/172). Causes included localized narrowings in the region of the anastomosis [9], significant narrowing along the graft [6], pre-existing additional stenoses in the native vessel, remote from the anastomosis and the lesion [7], stenoses not present preoperatively but seen postoperatively in the native vessel, remote from the anastomosis and original lesion [6], and separate obstructions of unbypassed branches [2]. While incomplete reperfusion is often unavoidable and is certainly preferable to total occlusion, evaluation based purely on patency rates is misleading, since it overlooks the fact that a significant proportion of patent grafts will not totally reperfuse the diseased vessel.

摘要

在评估冠状动脉旁路移植术时,通畅率实际上是成功的唯一标准。然而,这无法识别那些虽然通畅但未能使病变血管完全再灌注的移植物。对82例患者的172条旁路冠状动脉进行血管造影,结果证实126条(73%)通畅;然而,有30条移植物虽然通畅,但再灌注不完全,使得完全再灌注率仅为56%(96/172)。原因包括吻合口区域的局限性狭窄[9例]、移植物全程的显著狭窄[6例]、远离吻合口和病变处的自身血管中预先存在的额外狭窄[7例]、术前不存在但术后在远离吻合口和原病变处的自身血管中出现的狭窄[6例],以及未旁路分支的单独阻塞[2例]。虽然不完全再灌注往往不可避免,而且肯定比完全闭塞要好,但单纯基于通畅率的评估具有误导性,因为它忽略了一个事实,即相当一部分通畅的移植物不会使病变血管完全再灌注。

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