通过吸入放射性氙-113和动态发射断层扫描测量局部脑血流量。

Regional cerebral blood flow by radioxenon-113 inhalation and dynamic emission tomography.

作者信息

Lassen N A, Henriksen L, Paulson O B

出版信息

Prog Nucl Med. 1981;7:110-7.

Abstract

A rapidly rotating single photon tomograph is described for atraumatic and three-dimensional measurements of rCBF in ml/100 g/min. The instrument has a high sensitivity permitting the recording of the uptake and washout of xenon-133 from the human brain during and after inhalation of the gas at a concentration of 10 mCi/l for 1 min. The algorithm used to calculate rCBF is described, and clinical results in particular in stroke cases are presented. The rapidly rotating tomograph is better suited for the study of focal cerebral ischemia than the conventional stationary detectors because superposition of tissue layers is avoided.

摘要

本文描述了一种快速旋转的单光子断层扫描仪，用于对脑血流量（rCBF）进行无创三维测量，单位为毫升/100克/分钟。该仪器具有高灵敏度，能够记录在吸入浓度为10毫居里/升的氙-133气体1分钟期间及之后，氙-133在人脑中的摄取和清除情况。文中介绍了用于计算rCBF的算法，并给出了临床结果，特别是中风病例的结果。与传统的固定式探测器相比，快速旋转断层扫描仪更适合用于局灶性脑缺血的研究，因为它避免了组织层的叠加。