Lauritzen M, Henriksen L, Lassen N A
J Cereb Blood Flow Metab. 1981;1(4):385-7. doi: 10.1038/jcbfm.1981.42.
Regional cerebral blood flow (CBF) was studied in 16 normal adult volunteers during rest and in 10 the study was repeated during skilled hand movements. A fast-rotating ("dynamic"), single-photon emission computerized tomograph (ECT) with four detector heads was used. Xenon-133 was inhaled over a 1-min period at a concentration of 10 mCi/L. The arrival and washout of the radioisotope was recorded during four 1-min periods. Two slices, 2 cm thick, 7 and 12 cm above the orbitomeatal line were obtained in every study. CBF averaged 60 ml/100 g/min (SD +/- 11) in the lower slice and 51 ml/100 g/min (SD +/- 13) in the upper slice. A symmetric pattern comparing right to left sides was found in both slices. Finger tapping and writing with the right hand increased CBF in specific areas of the upper slice: in the contralateral hand area by 35 +/- 15% (p less than 0.025), and in the supplementary motor area on both sides by 34 +/- 15% (p less than 0.025).
