Salkie M L, Kelker D H
Vox Sang. 1981 Nov-Dec;41(5-6):282-6. doi: 10.1111/j.1423-0410.1981.tb01050.x.
Aliquots of 213 specimens were assayed for C3, C4 and CH50. A graphical presentation of the data was obtained by a block diagram. This showed a generally flat plane with good agreement to quoted normal ranges. Only 2 of 68 specimens with C3 and C4 normal have a low CH50. If either the C3 or C4 is low then the CH50 may be normal or even high, but if both fractions are low then so is the Ch50. A low CH50 can occur with both C3 and C4 in the normal range or even higher. This implicates other complement factors as being deficient with a sufficiently high occurrence rate to require that the CH50 be kept as a routine laboratory procedure.
对213份样本的等分试样进行了C3、C4和CH50检测。通过方框图获得了数据的图形展示。这显示出一个总体较为平坦的平面，与引用的正常范围吻合良好。在68份C3和C4正常的样本中，只有2份CH50较低。如果C3或C4中有一个较低，那么CH50可能正常甚至较高，但如果两个组分都低，那么CH50也低。CH50低可能发生在C3和C4都在正常范围内甚至更高的情况下。这意味着其他补体因子存在足够高发生率的缺陷，需要将CH50检测作为常规实验室程序保留。
