Amess J A, Burman J F, Murphy M F, Paxton A M, Mollin D L
Clin Lab Haematol. 1981;3(3):231-7. doi: 10.1111/j.1365-2257.1981.tb01337.x.
Two patients are reported who developed peripheral blood abnormalities and marked megaloblastic bone marrow change within eleven days of cardiac bypass surgery. The patients were shown to have unsuspected mild vitamin B12 deficiency due to Addisonian pernicious anaemia. The megaloblastic changes were presumed to be precipitated by the increased demand for erythrocytes and platelets after surgery.
据报道，两名患者在心脏搭桥手术后11天内出现外周血异常和明显的巨幼细胞性骨髓改变。结果显示，这两名患者因艾迪生病性恶性贫血而存在未被怀疑的轻度维生素B12缺乏。巨幼细胞性改变被推测是由术后对红细胞和血小板需求增加所引发的。
