新生儿脑室内出血时颅内压和脑动脉搏动血流测量

Intracranial pressure and cerebral arterial pulsatile flow measurement in neonatal intraventricular hemorrhage.

作者信息

Bada H S, Miller J E, Menke J A, Menten T G, Bashiru M, Binstadt D, Sumner D S, Khanna N N

出版信息

J Pediatr. 1982 Feb;100(2):291-6. doi: 10.1016/s0022-3476(82)80657-4.

Abstract

We examined the clinical significance of noninvasive intracranial pressure measurements and pulsatility indices in 74 infants with confirmed IC-IVh. The intracranial pressure measurements were obtained using the applanation principle, and the pulsatility indices were calculated from the Doppler flow velocity tracings of the anterior cerebral artery. Fifty-three infants (71.6%) who died had a significantly lower birth weight and gestational age than those who survived. Survival rate decreased significantly with increased intracranial pressure (P less than 0.0002) and increased pulsatility indices (P less than 0.0001). We found no significant relationship between outcome and the size of IC-IVH demonstrated by CT scan. Birth weight, intracranial pressure measurements, and cerebral arterial pulsatile flow changes appear to be major prognostic indicators in neonatal IC-IVH.

摘要

我们研究了74例确诊为IV级颅内出血（IC-IVh）婴儿的无创颅内压测量及搏动指数的临床意义。颅内压测量采用压平原理获得，搏动指数由大脑前动脉的多普勒血流速度描记图计算得出。死亡的53例婴儿（71.6%）出生体重和胎龄显著低于存活婴儿。随着颅内压升高（P<0.0002）和搏动指数增加（P<0.0001），存活率显著降低。我们发现CT扫描显示的IC-IVH大小与预后无显著关系。出生体重、颅内压测量及脑动脉搏动血流变化似乎是新生儿IC-IVH的主要预后指标。