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驯鹿心脏的左心室容积与功能。

Left ventricular volumes and functioning of the reindeer heart.

作者信息

Timisjärvi J

出版信息

Basic Res Cardiol. 1978 Jul-Aug;73(4):355-64. doi: 10.1007/BF01906517.

Abstract

Left ventricular volumes were measured by cineangiocardiography in 56 sessions on 25 reindeer, together with determinations of arterial pressure and blood oxygen saturation. The heart rate with the animal kept lying on the sternum at rest was 50 b/min, the aortic blood oxygen saturation 94 to 98% and the aortic blood pressure 153/130/115 mm Hg. The left ventricular end-diastolic volume was 3.4 ml/kg of b.w., stroke volume 2.6 ml/kg, cardiac output 133 ml/kg . min, and ejection fraction 76%. If the animal was placed on its side the aortic blood oxygen saturation decreased by 2 to 3 per cent, end-diastolic volume rose 10%, stroke volume 25%, cardiac output nearly 30% and ejection fraction 14%. The heart rate and cardiac output increased in hypoxemia, but the end-diastolic and stroke volumes simultaneously decreased. If the aortic blood pressure rose during hypoxia, the end-diastolic and stroke volumes increased, while the ejection fraction first increased and then decreased again. In normoxia a rise in aortic blood pressure was associated with decreased end-diastolic and stroke volumes and ejection fraction. An increased heart rate at rest was followed by increased cardiac output, but decreased end-diastolic and stroke volumes and ejection fraction.

摘要

对25头驯鹿进行了56次心血管造影,测量左心室容积,并测定动脉压和血氧饱和度。动物静卧于胸骨时的心率为50次/分钟,主动脉血氧饱和度为94%至98%,主动脉血压为153/130/115毫米汞柱。左心室舒张末期容积为3.4毫升/千克体重,每搏输出量为2.6毫升/千克,心输出量为133毫升/千克·分钟,射血分数为76%。如果将动物侧卧,主动脉血氧饱和度会下降2%至3%,舒张末期容积增加10%,每搏输出量增加25%,心输出量增加近30%,射血分数增加14%。低氧血症时心率和心输出量增加,但舒张末期和每搏输出量同时减少。如果缺氧时主动脉血压升高,舒张末期和每搏输出量增加,而射血分数先增加后又下降。在正常氧合状态下,主动脉血压升高与舒张末期、每搏输出量和射血分数降低有关。静息时心率增加后,心输出量增加,但舒张末期、每搏输出量和射血分数降低。

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