Timisjärvi J, Hirvonen L
Basic Res Cardiol. 1978 Sep-Oct;73(5):497-505. doi: 10.1007/BF01906529.
Right heart catheterizations were performed in 56 sessions on 25 reindeer with determinations of blood pressure and oxygen saturation. Cardiac output was calculated from cineangiocardiograms. When the animals were placed in prone position, heart rate was about 50/min, mixed venous blood oxygen saturation 68 to 72%, right ventricular systolic pressure 27 mmHg, pulmonary arterial pressure 25/16/11 mmHg, pulmonary arterial wedge pressure 6--8 mmHg and pulmonary transfer time 4 to 5 cardiac cycles. When the animals were placed on their side, the heart rate rose to 90 b/min, mixed venous blood oxygen saturation decreased by about 4% and the right ventricular and pulmonary arterial pressures increased by about 10 mmHg; pulmonary arterial wedge pressure did not change. Hypoxemia led to an increase in heart rate, cardiac output and pulmonary arterial pressure; the latter two measures tended to increase whenever the heart rate increased. Under the conditions stated here, an increased pulmonary vascular resistance was calculated when pulmonary arterial pressure was increased.
对25只驯鹿进行了56次右心导管插入术,测定了血压和血氧饱和度。心输出量由心血管造影电影计算得出。当动物处于俯卧位时,心率约为50次/分钟,混合静脉血氧饱和度为68%至72%,右心室收缩压为27 mmHg,肺动脉压为25/16/11 mmHg,肺动脉楔压为6 - 8 mmHg,肺循环时间为4至5个心动周期。当动物侧卧时,心率升至90次/分钟,混合静脉血氧饱和度下降约4%,右心室和肺动脉压升高约10 mmHg;肺动脉楔压无变化。低氧血症导致心率、心输出量和肺动脉压升高;后两项指标往往随心率增加而升高。在此所述条件下,当肺动脉压升高时,计算得出肺血管阻力增加。