Thornton J W, Hess C A, Cassingham V, Bartlett R H
Burns Incl Therm Inj. 1982 Jan;8(3):156-60. doi: 10.1016/0305-4179(82)90079-1.
The effects of the topical application of epidermal growth factor (EGF) on the healing of partial-thickness scald burns in rats was evaluated. Time to complete healing, the rate of healing, daily percentage weight change, and cell growth were the measured parameters. We were able to demonstrate an insignificant healing advantage with the topical application of EGF, by itself or in combination with silver sulphadiazine. This insignificant healing advantage does not warrant clinical evaluation.
评估了局部应用表皮生长因子（EGF）对大鼠浅Ⅱ度烫伤愈合的影响。测量的参数包括完全愈合时间、愈合速率、每日体重变化百分比和细胞生长情况。我们发现，单独或与磺胺嘧啶银联合局部应用EGF，其愈合优势并不显著。这种不显著的愈合优势不值得进行临床评估。
